Berberine May Ease Symptoms of Anxiety and Depression — And Much More

(Dr. Mercola) Berberine — a yellow-colored alkaloid compound found in several different plants, including European barberry, goldenseal, goldthread, Oregon grape and tree turmeric — has antibacterial, anti-inflammatory, antiproliferative, antidiarrheal, antineoplastic, antidiabetic and immune-enhancing1 properties. It has a long history of use in traditional medicine, including traditional Chinese medicine, and many of its historical uses now have scientific backing.

For example, it’s effective against a wide range of bacteria, protozoa and fungi, and is commonly used to treat gastrointestinal issues, including traveler’s diarrhea and that from food poisoning. Having similar mechanisms of action as the drug metformin, berberine can also be used as an oral hypoglycemic for Type 2 diabetics.

Related: Berberine

It’s helpful against seasonal allergies and even helps combat metastatic stem cells and heart failure. Many integrative health practitioners swear by berberine as a general health supplement due to its ability to address such a wide variety of maladies.2 As noted by Dr. Michael Murray:3

“… I think [berberine] is poised to be the biggest thing in the natural product industry … Here is why: Berberine has been shown to:

  • Produce results in clinical trials in improving Type 2 diabetes on par or better than conventional drugs including metformin.
  • Improve blood lipid levels better than statins.
  • Lower blood pressure in many subjects as well as any class of antihypertensive medication.
  • Improve liver function and promote anti-obesity effects.
  • Exert significant beneficial effects on digestive health and the microbiome.
  • Produce very encouraging experimental data in a wide range of modern health issues including cancer, Alzheimer’s disease, Parkinson’s disease and others.”

What Makes Berberine Such a Powerful Remedy?

Many of berberine’s health benefits4 have been linked to its ability to activate adenosine monophosphate-activated protein kinase (AMPK).5 AMPK is an enzyme inside your body’s cells. It’s sometimes referred to as a “metabolic master switch” because it plays an important role in regulating metabolism.6

Related: Insomnia – A Comprehensive Look with Natural Remedies

Low AMPK has been linked to insulin resistance, mitochondrial dysfunction, obesity, neurodegeneration and chronic inflammation — all of which lay the groundwork for a wide variety of serious chronic diseases. In an article discussing the clinical uses of berberine for metabolic syndrome and Type 2 diabetes, the Natural Medicine Journal highlights its effect on AMPK:7

“AMPK induces a cascade of events within cells that are all involved in maintaining energy homeostasis… AMPK regulates an array of biological activities that normalize lipid, glucose and energy imbalances. Metabolic syndrome occurs when these AMPK-regulated pathways are turned off, triggering a syndrome that includes hyperglycemia, diabetes, lipid abnormalities and energy imbalances …

AMPK helps coordinate the response to these stressors, shifting energy toward cellular repair, maintenance or a return to homeostasis and improved likelihood of survival. The hormones leptin and adiponectin activate AMPK. In other words, activating AMPK can produce the same benefits as exercise, dieting and weight loss — the lifestyle modifications considered beneficial for a range of maladies …

One way to appreciate berberine’s potential is to think of it as having the same effect on a patient as increasing exercise while at the same time restricting calorie intake. Think of the effects of AMPK suppression as similar to those of eating a high-calorie diet while leading a very sedentary lifestyle.”

Berberine Helps Ease Anxiety and Depression

AMPK is also an important neuroprotector. As explained in the Journal of Neurochemistry,8 “AMPK senses metabolic stress and integrates diverse physiological signals to restore energy balance. Multiple functions are indicated for AMPK in the [central nervous system] …” Berberine also benefits brain health and psychological well-being by increasing key neurotransmitters.

Related: Holistic Guide to Healing the Endocrine System and Balancing Our Hormones

A number of studies have demonstrated berberine’s usefulness against anxiety and depression, in part by inhibiting monoamine oxidase, an enzyme that breaks down serotonin, noradrenaline and dopamine in your brain. These neurotransmitters play important roles in mood and have been implicated in depression.

An Indian study9 published in 2008 confirmed berberine has antidepressant effects, reversing “behavioral despair” in stressed rats. Interestingly, the effects were not dose-dependent. Even low doses had a beneficial effect. According to the authors:

“Berberine (5 mg/kg, i.p.) following its acute administration in mice resulted in increased levels of norepinephrine (31 percent), serotonin (47 percent) and dopamine (31 percent) in the whole brain. Chronic administration of berberine (5 mg/kg, i.p.) for 15 days significantly increased the levels of norepinephrine (29 percent), serotonin (19 percent) as well as dopamine (52 percent) …

[A]t higher dose (10 mg/kg, i.p.), there was no change in the norepinephrine (12 percent) levels but a significant increase in the serotonin (53 percent) and dopamine (31 percent) levels was found.”

A similar study by South Korean researchers found berberine was helpful in treating post-traumatic stress disorder (PTSD). As in the Indian study, rats exposed to prolonged stress exhibited significantly reduced anxiety-driven behaviors after receiving berberine. They were also better able to complete complex navigational tests.

Most remarkable of all, berberine was shown to “restore the main neurochemical abnormalities in the brains of rats in the PTSD model” — a rather surprising effect that “supports a central mechanism of action that berberine heals brains damaged by severe stress or fear.”10

Berberine Eases Side Effects Associated With Drug Withdrawal

Berberine has also been shown to activate Sigma1 receptors, a subclass of opioid receptors that react to morphine and similar substances — including those produced naturally in your body — and inhibits glutamate, thereby improving anxiety and depression.11Sigma1 receptors play a role in oxidative stress, the functioning of your nervous system and the survival of neurons, and as such are believed to influence neuropsychiatric problems, including psychotic conditions.12

Related: Natural Remedies for Depression

A study13 published in the Korean Journal of Physiology and Pharmacology assessed berberine’s effect on not just depression and anxiety but also on the noradrenergic system. Here, they used morphine-addicted rats to see whether berberine might ease morphine withdrawal — symptoms of which often include depression and anxiety. As explained by the authors:

“Male rats were exposed to chronic, intermittent, escalating morphine (10~50 mg/kg) for 10 days. After the last morphine injection, depression- and anxiety-like behavior associated with morphine discontinuation persisted for at least three days during withdrawal without any change in ambulatory activity. Daily berberine administration significantly decreased immobility in the forced swimming test and increased open-arm exploration in the elevated plus maze test …

Taken together, these findings demonstrated that berberine administration significantly reduced morphine withdrawal-associated behaviors … possibly through modulation of hypothalamic corticotrophin-releasing factor and the central noradrenergic system. Berberine may be a useful agent for treating or alleviating complex withdrawal symptoms and preventing morphine use relapses.”

Berberine Supports Gut Health and Much More

Berberine has also been shown to support a healthy gastrointestinal tract and microbiome in a number of different ways, and this too can have a beneficial impact on your mood and mental health. There’s ample research showing your gut health plays a very important role in your brain health, and can influence your mood for better or worse. As for improving your gut health, studies have shown berberine helps:

Prevent diarrhea by delaying the amount of time it takes for food to pass through your small intestine14
Lower your risk of leaky gut15
Protect against gut damage caused by high alcohol consumption16
Lower intestinal inflammation caused by inflammatory cytokines17
Preferentially nourish microbes that produce beneficial short-chain fatty acids, known to have many health benefits18
Improve symptoms of fatty liver disease by normalizing the gut microbiome19
The normalization of gut bacteria also resulted in lower body weight, lower serum levels of lipids, lower glucose and insulin levels, and the normalization of insulin resistance20

Drug Interactions

While berberine is quite safe and well-tolerated, it may be contraindicated if you’re taking medications.21 For example, berberine may hinder absorption of tetracycline and other similar antibiotics, rendering them ineffective. Also, because berberine significantly inhibits CYP3A enzymes — enzymes needed to metabolize most drugs — it can lower the clearance of medications, which in turn can augment their effect. This can lead to overdose, the risks of which will vary depending on the drug in question.

Related: Sugar Leads to Depression – World’s First Trial Proves Gut and Brain are Linked (Protocol Included)

Berberine inhibits CYP3A just like curcumin, which impairs phase 2 detoxification, where your body makes toxins water soluble so they can be excreted. So, this would not be supplements to use during fasting where you have large lipolysis and liberation of stored toxins that need to be metabolized.

Because of all its benefits, I have been taking berberine for over two years. However, because it is a potent alkaloid, I believe it needs to be cycled. So, I take it for a week then take a week off. Alternatively, you can skip it on the weekends. The general principle is cycling, just like one does with the ketogenic diet. It is not wise to be continuously ketogenic.

Also, as noted by Murray:22 “Berberine … enhances the effects of oral hypoglycemic drugs used in the treatment of Type 2 diabetes through its multitude of antidiabetic effects. People on oral hypoglycemic drugs should monitor blood glucose levels if taking berberine and adjust their dosage of their medications as needed and under the care of a medical professional.” I tell virtually everyone taking metformin to switch to berberine as it is far safer.

New Insight Into How “Gut Feelings” Affect Mental Health, Depression And Anxiety

(Natural Blaze by Alex Pietrowski) In recent years, the study of causes and treatments of depression has uncovered a link to the health of the microbiome within the body’s digestive system. The hypothesis is that the presence or absence of healthy digestive bacteria affects the way the brain functions, and new research by a Florida State University neuroscientist sheds more insight into this.

The findings by research and psychology professor Linda Rinaman point to a very important connection between the gut and the brain, identifying pathways that help to understand why so-called ‘gut feelings’ have a powerful influence on emotions, mood and decision-making.

Related: Sugar Leads to Depression – World’s First Trial Proves Gut and Brain are Linked (Protocol Included)

We expect these lines of research will help us better understand how gastrointestinal functions contribute to both normal and disordered mental function. ~Linda Rinaman

Her research looked at pathways between the gut and the brain in mammals, noting how feelings generated within the gut move into the brain, indicating that some ‘gut-feelings’ are a red flag and thereby may be a fair indicator of healthy mood and mental states.

In the human body, the vagus nerve acts as the pathway between the brain and gut. The nerve is the body’s largest and most extensive nerve, translating and carrying messages between the gastrointestinal tract and the brain. If the gut is operating optimally, the brain is cued to respond more positively. Food and proper supplementation are important factors.

Related: Candida, Gut Flora, Allergies, and Disease

Scientific and anecdotal evidence suggests a poor diet can cause those protective, cautionary signals to get out of whack, leading to altered mood and behavior. For example, Rinaman said, a high-fat diet can promote a low-grade inflammatory response in the GI tract, changing vagal signals and possibly exacerbating symptoms of anxiety, depression or other disturbed mental states.

Rinaman said the types of bacteria within your gut are shaped by your diet, and those bacteria can affect your emotional and cognitive state. [Source]

The emotional significance of the vagus nerve is discussed further:

Research indicates that a healthy vagus nerve is vital in experiencing empathy and fostering social bonding, and it is crucial to our ability to observe, perceive, and make complex decisions. Tests have revealed that people with impaired vagal activity have also been diagnosed with depression, panic disorders, Post Traumatic Stress Disorder (PTSD), irritable bowel syndrome, anxiety, panic disorders, violent mood swings, fibromyalgia, early Alzheimer’s and obesity. Given the state of society today and the vast array of dis-eases associated with unhealthy Vagus Nerves, it doesn’t take a medical doctor to conclude that by healing our collective Vagus Nerves, we can heal a lot of societies woes.

Scientists have discovered that artificial Vagus Nerve Stimulation (VNS), through electrical impulses via a surgically implanted pacemaker like device, shows promising results in reducing depression, anxieties and even conditions such as epilepsy and obesity. VNS has also shown positive effects in promoting weight-loss as the signals to the brain of ‘fullness’ are more easily transmitted. But what if there were a less intrusive and more natural way to stimulate and heal the Vagus Nerve? ~Frank Huguenard

Related: Gluten, Candida, Leaky Gut Syndrome, and Autoimmune Diseases

The important takeaway here is that supporting healthy gut function along with healthy function of the vagus nerve is being demonstrated to be a potentially very potent way of holistically approaching treatment of depression and anxiety.

Evidence shows that modifying the diet, perhaps by consuming probiotics, can impact your mood and behavioral state. That’s very clear in animal and human studies. ~Linda Rinaman

Real Food Is a Potent Ally Against Depression

(Dr. Mercola) According to the World Health Organization, depression is now the leading cause of ill health and disability worldwide,1,2 affecting an estimated 322 million people globally, including more than 16 million Americans, 6 million of which are seniors.3 Statistics also reveal we’re not being particularly effective when it comes to prevention and treatment. Worldwide, rates of depression increased by 18 percent between 2005 and 2015.4

If you or someone you love is struggling with depression or some other mental health problem, remember that your diet is a foundational aspect that must not be overlooked. As noted in a 2015 study5 published in the medical journal Lancet:

“Although the determinants of mental health are complex, the emerging and compelling evidence for nutrition as a crucial factor in the high prevalence and incidence of mental disorders, suggests that diet is as important to psychiatry as it is to cardiology, endocrinology and gastroenterology.”

Related: Sugar Leads to Depression – World’s First Trial Proves Gut and Brain are Linked (Protocol Included)

The Compelling Link Between Food and Mood

Recent research6,7,8 looking at the effects of the antihypertensive DASH diet on mental health concluded this kind of dietary pattern, which is low in sugar and high in fresh fruits and vegetables, can help reduce the risk of depression in seniors. Overall, people who followed the DASH diet were 11 percent less likely to develop depression over the following six years, whereas those following a standard Western diet, high in red meat and low in fruits and vegetables, had the highest rates of depression.

It’s worth noting that while many conventional experts recommend the DASH diet, it is not necessarily ideal for optimal health, as it also promotes whole grains and low-fat foods, including low-fat dairy. Healthy fats, including saturated animal and plant fats and animal-based omega-3, are quite crucial for optimal brain health. I believe the reason the DASH diet produces many beneficial results is because it is low in sugar and high in unprocessed foods — not because it’s low in fat.

Other studies have shown that unprocessed foods, especially fermented foods, help optimize your gut microbiome, thereby supporting optimal mental health,9,10 whereas sugar, wheat (gluten) and processed foods have been linked to a greater risk for depression, anxietyand even suicide. The primary information highway between your gut and your brain is your vagus nerve, which connects the two organs.11

Related: Natural Remedies for Depression

Your gut also communicates to your brain via the endocrine system in the stress pathway (the hypothalamus, pituitary and adrenal axis), and by producing mood-boosting neurotransmitters like serotonin, dopamine and gamma-aminobutyric acid or GABA. These communication links help explain why your gut health has such a significant impact on your mental health.

The Strong Link Between Sugar and Depression

A number of food ingredients can cause or aggravate depression, but one of the most significant is sugar, particularly refined sugar and processed fructose.12 For example, in one study, men consuming more than 67 grams of sugar per day were 23 percent more likely to develop anxiety or depression over the course of five years compared to those whose sugar consumption was less than 40 grams per day (which is still far higher than the 25 grams per day recommended for optimal health).13

This held true even after accounting for other contributing factors, such as socioeconomic status, exercise, alcohol use, smoking, other eating habits, body weight and general physical health. Lead author Anika Knüppel,14 a research student in the department of epidemiology and public health at University College London, commented on the findings, saying:15

“Sweet food has been found to induce positive feelings in the short-term. People experiencing low mood may eat sugary foods in the hope of alleviating negative feelings. Our study suggests a high intake of sugary foods is more likely to have the opposite effect on mental health in the long-term.”

Research16 published in 2002, which correlated per capita consumption of sugar with prevalence of major depression in six countries, also found “a highly significant correlation between sugar consumption and the annual rate of depression.” A Spanish study17 published in 2011 linked depression specifically to consumption of baked goods.

Those who ate the most baked goods had a 38 percent higher risk of depression than those who ate the least. This makes sense when you consider baked goods contain both processed grains and added sugars.

Related: Healthy Alternative Sugars and More

How Sugar Wreaks Havoc on Your Mood and Mental Health

Sugar has been shown to trigger depression and other mental health problems through a number of different mechanisms, including the following:

Feeding pathogens in your gut, allowing them to overtake more beneficial bacteria.
Suppressing activity of a key growth hormone in your brain called brain-derived neurotrophic factor (BDNF). BDNF levels are critically low in both depression and schizophrenia, and animal models suggest this may actually be a causative factor.
Triggering a cascade of chemical reactions in your body that promote chronic inflammation, which over the long term disrupts the normal functioning of your immune system and wreaks havoc on your brain.
Contributing to insulin and leptin resistance, which also plays a significant role in your mental health.
Affecting dopamine, a neurotransmitter that fuels your brain’s reward system18 (hence sugar’s addictive potential19,20,21) and is known to play a role in mood disorders.22
Damaging your mitochondria, which can have bodywide effects. Your mitochondria generate the vast majority of the energy (adenosine triphosphate or ATP) in your body.

When sugar is your primary fuel, excessive reactive oxygen species (ROS) and secondary free radicals are created, which damage cellular mitochondrial membranes and DNA. As your mitochondria are damaged, the energy currency in your body declines and your brain will struggle to work properly.

Healthy dietary fats, on the other hand, create far fewer ROS and free radicals. Fats are also critical for the health of cellular membranes and many other biological functions, including and especially the functioning of your brain.

Among the most important fats for brain function and mental health are the long-chained animal-based omega-3 fatsDHA and EPA. Not only are they anti-inflammatory, but DHA is actually a component in every cell of your body, and 90 percent of the omega-3 fat found in brain tissue is DHA.

Eating Real Food Is Key

A paper23 published in Nutritional Neuroscience last year looked at evidence from laboratory, population research and clinical trials to create “a set of practical dietary recommendations for the prevention of depression, based on the best available current evidence.” According to this paper, the published evidence reveals five key dietary recommendations for the prevention of depression:

  • Following a “traditional” dietary pattern such as the Mediterranean, Norwegian or Japanese diet
  • Increasing consumption of antioxidant-rich fruits, vegetables, legumes, wholegrain cereals, nuts and seeds (note that autoimmune diseases are rampant and whole grains and legumes are loaded with lectins and best avoided. See my interview with Dr. Steven Gundry for more details)
  • Eating plenty of omega-3-rich foods
  • Replacing unhealthy processed foods with real, wholesome nutritious foods
  • Avoiding processed foods, fast food, commercial baked goods and sweets

Processed Foods Are Problematic in More Ways Than One

Three brain- and mood-wrecking culprits you’ll automatically avoid when avoiding processed foods are added sugars, artificial sweeteners24 and processed vegetable oils — harmful fats known to clog your arteries and cause mitochondrial dysfunction. Gluten also appears to be particularly problematic for many. If you’re struggling with depression or anxiety, you’d be well-advised to experiment with a gluten-free diet.

Certain types of lectins, especially wheat germ agglutinin (WGA), are also known for their psychiatric side effects. WGA can cross your blood brain barrier25 through a process called “adsorptive endocytosis,” pulling other substances with it. WGA may attach to your myelin sheath26 and is capable of inhibiting nerve growth factor,27 which is important for the growth, maintenance and survival of certain target neurons.

Processed foods are also a significant source of genetically engineered (GE) ingredients and toxic herbicides like Roundup. In addition to being toxic and potentially carcinogenic, glyphosate, the active ingredient in Roundup, has been shown to preferentially decimate beneficial gut microbes. Many grains need to dry in the field before being harvested, and to speed that process, the fields are doused with glyphosate a couple of weeks before harvest.

As a result of this practice, called desiccation, grain-based products tend to contain rather substantial amounts of glyphosate. This reason alone is enough to warrant a grain-free diet, but if you do choose to eat whole grain products, make sure it’s organic to avoid glyphosate contamination.

Your beverage choices may also need an overhaul, as most people drink very little pure water, relying on sugary beverages like sodas, fruit juices, sports drinks, energy drinks and flavored water for their hydration needs. None of those alternatives will do your mental health any favors.

Anti-Inflammatory Diet Protects and Supports Good Mental Health

As mentioned above, one of the mechanisms by which good nutrition bolsters mental health is by cutting down inflammation in your body, and a high-sugar diet is exceptionally inflammatory. A number of studies have linked depression with chronic inflammation.28,29

For example, a study30 published in the Journal of Clinical Psychiatry in 2016 concluded that depressed patients had 46 percent higher levels of the inflammatory marker C-reactive protein in their blood. Interestingly, they also had 16 percent lower levels of low fractional exhaled nitric oxide, which adds further support for doing exercises that boost nitric oxide cycling, such as the Nitric Oxide Dump exercise. As explained in the study:

“Nitric oxide (NO), in addition to being an inflammatory mediator, is also a neurotransmitter at the neuron synapses. It modulates norepinephrine, serotonin, dopamine and glutamate and thus is speculated to play a role in the pathogenesis of depression. Nitric oxide is also currently seen as a marker of airway inflammation and can be measured during exhalation.

Fractional exhaled nitric oxide (FeNO) may represent both constitutive and inducible NO. Small studies suggest that subjects with depressed mood have low levels of FeNO … Subjects with depression also have low levels of plasma and platelet NO. The low systemic levels of NO have been postulated to be responsible for the increased risk of cardiovascular events observed in subjects with depression, as NO produces vasodilatation …

In summary, this large population-based study found that depression is associated with high levels of CRP and low levels of FeNO. These findings corroborate the premise that inflammation could play a role in the pathophysiology of major depression and that major depression may be seen as a psychoneuroimmunological disorder.”

Related:

Four Powerful Dietary Interventions

In addition to transitioning from a diet of processed fare to real food, consider:

Implementing a cyclical ketogenic diet, high in healthy fats, low in net carbs with moderate amounts of protein. This kind of diet will optimize your mitochondrial function, which has significant implications for mental health. In fact, one noticeable effect of nutritional ketosis is mental clarity and a sense of calm. The reason for this welcome side effect has to do with the fact that when your body is able to burn fat for fuel, ketones are created, which is the preferred fuel for your brain.

Intermittent fasting will also help optimize your brain function and prevent neurological problems by activating your body’s fat-burning mode, preventing insulin resistance and reducing oxidative stress and inflammation, the latter of which has been identified as a causative factor in depression.31,32

While you may achieve some of the benefits from intermittent fasting simply by respecting the time boundaries, regardless of the foods you consume, it is far better if you consume high-quality unprocessed food.

Since you’ll be eating less, it’s vitally important that you get proper nutrition. Healthy fats are essential because intermittent fasting pushes your body to switch over to fat-burning mode. Particularly if you begin to feel tired and sluggish, it may be a sign that you need to increase the amount of healthy fat in your diet.

Water fasting. Once you’re starting to burn fat for fuel, gradually increase the length of your daily intermittent fasting to 20 hours per day. After a month of 20-hour daily fasting, you’re likely in good metabolic shape and able to burn fat as fuel. At that point, you can try a four or five-day water-only fast.

I now do a quarterly five-day fast, as I believe this is one of the most powerful metabolic health interventions out there. A five-day fast will effectively clean out senescent cells that have stopped duplicating due to aging or oxidative damage, which would otherwise clog up your optimal biologic function by causing and increasing inflammation.

Exercise and get regular movement throughout your day. Exercise is one of the most effective antidepressant strategies out there, beating most medical interventions for depression.

Electromagnetic Field Exposures Could Be Wreaking Havoc With Your Mental Health

Another foundational strategy to prevent or treat depression and anxiety is to limit exposure to electromagnetic fields (EMFs). Studies have linked excessive EMF exposure to an increased risk of both depression and suicide.33 Addiction to or “high engagement” with mobile devices can also trigger depression and anxiety, according to recent research from the University of Illinois.34

Research35 by Martin Pall, Ph.D., reveals a previously unknown mechanism of biological harm from microwaves emitted by cellphones and other wireless technologies, which helps explain why these technologies can have such a potent impact on your mental health. Embedded in your cell membranes are voltage gated calcium channels (VGCCs), which are activated by microwaves. When activated, a cascade of biochemical effects occurs that result in the creation of extremely destructive hydroxyl free radicals.

Hydroxyl free radicals decimate mitochondrial and nuclear DNA, their membranes and proteins. The end result is mitochondrial dysfunction, which we now know is at the heart of most chronic disease. The tissues with the highest density of VGCCs are your brain, the pacemaker in your heart and male testes. Hence, health problems such as Alzheimer’s, anxiety, depression, autism, cardiac arrhythmias and infertility can be directly linked to excessive microwave exposure.

So, if you struggle with anxiety or depression, be sure to limit your exposure to wireless technologies, in addition to addressing your diet and exercise. Simple measures include turning your Wi-Fi off at night, not carrying your cellphone on your body and not keeping portable phones, cellphones and other electric devices in your bedroom. The electric wiring inside your bedroom walls is probably the most important source to address.

Your best bet here is to turn off the power to your bedroom at night. This will work if there are no adjacent rooms. If there are, you may need to shut those rooms off also. The only way to know would be to measure the electric fields. For additional lifestyle guidelines that can help prevent and/or treat depression, see the nondrug solutions section at the end of this previous article on depression.

Mercury Dental Amalgams Are Linked To Chronic Illness, Fatigue, Depression And Anxiety

(Natural Blaze By Brandon Turbeville) It might seem surprising to some but in 2017 there is still debate in the medical community as to whether or not dental mercury amalgams are safe.

Despite voluminous amounts of evidence suggesting that mercury fillings are incredibly toxic, many dentists and medical doctors maintain that there is no major side effects from their usage. However, an article published in Neuroendocrinology Letters back in 2014 shows that the mercury filling hold outs are standing in stark opposition to the evidence.

The researchers for the article set out to review the evidence surrounding a possible link between mercury exposure from dental amalgams and certain chronic illnesses such as fibromyalgia, chronic fatigue syndrome, anxiety, depression and suicide.

Must Read: Mercury Fillings, Root Canals, Cavitations – What You Need to Know

Studies had already previously shown that chronic mercury exposure is directly associated with a variety of health issues, especially depression, anxiety and fatigue. Interestingly enough, these are some of the main symptoms associated with fibromyalgia and chronic fatigue syndrome.

Other studies have shown that the [careful, staggered] removal of dental amalgams have shown an improvement in these symptoms.

As the authors of the study stated,

Although the issue of amalgam safety is still under debate, the preponderance of evidence suggests that Hg exposure from dental amalgams may cause or contribute to many chronic conditions. Thus, consideration of Hg toxicity may be central to the effective clinical investigation of many chronic illnesses, particularly those involving fatigue and depression.

Related:  Still Have Candida? How Mercury Fillings Cause Candida Overgrowth

The fact that there would still be some hold outs despite the wide availability of viable alternatives, calls into question the sanity of some medical professionals. Even the World Health Organization – not known for its revolutionary or natural approach to health – has clearly stated that adverse health effects from mercury include impaired vision and hearing, insomnia, developmental deficits during fetal development, developmental delays during childhood, attention deficit, emotional instability, paralysis, and tremors.

Recommended Reading:

Depression Doubles the Risk of Death From Coronary Artery Disease, Finds Research

(Independent) Depression appears to double the chance of dying in any given year for patients with coronary artery disease, according to a new study.

 The researchers said such mental distress was a “stronger risk factor” than age, having had a heart attack, or diabetes.
Related: Lower Cholesterol and prevent Heart Disease Without Drugs
The effect was seen if the person was depressed before or after diagnosis of the disease.

Dr. Heidi May, a cardiovascular epidemiologist at Intermountain Medical Centre Heart Institute in Salt Lake City, said: No matter how long or how short it was, patients were found to have twice the risk of dying compared to those who didn’t have a follow-up diagnosis of depression.

Depression was the strongest risk factor for dying, compared to any other risk factors we evaluated. That included age, heart failure, diabetes, high blood pressure, kidney failure, or having a heart attack or stroke.

We’ve completed several depression-related studies and been looking at this connection for many years.

The data just keeps building on itself, showing that if you have heart disease and depression and it’s not appropriately treated in a timely fashion, it’s not a good thing for your long-term wellbeing.”

Of more than 2,600 patients who became clinically depressed about 27 per cent did so within a year of being diagnosed with the disease. The figure was 37 per cent after five years.

And while depression seems to make the condition worse, being diagnosed is also a reason why some patients become depressed.

The reason why the chance of dying increased was not revealed by the study, but Dr. May said it was possible patients were not following their treatment plans as closely as people in good mental health. She said,

We know people with depression tend to be less compliant with medication on average and probably in general aren’t following healthier diets or exercise regimens.

They tend to do a poorer job of doing things that are prescribed than people without depression. That certainly doesn’t mean you’re depressed so you’re going to be less compliant, but in general, they tend to follow those behaviours.”

 She added that depression can also cause physiological changes to the body, which could also be a factor.
Related: Natural Approaches to Combat Depression

Dr. May urged the medical community to take depression seriously when treating coronary artery disease.

Patients who have depression need to be treated to improve not only their long-term risks but their quality of life.”