Category: Diet

Epidemic Numbers of People Suffering From Constipation

(Dr. Mercola) For most people, an occasional bout of constipation is a minor aggravation. However, this is not the case for the nearly 15 percent of the U.S. population suffering from chronic constipation.1 This means 63 million people have difficulty passing hard, dry, lumpy stool, suffer from feeling bloated, have abdominal pain or feel as if there is something stuck in their rectum or intestines.2

For many, the topic of their bowel movements is a private matter. This makes understanding and learning about the actual mechanics of how stool is produced and eliminated difficult, as many don’t find it a topic they want to discuss, even with their physicians.

The number of stools you have each week is closely linked to the types of food you eat, the amount of exercise you get and your hydration status. While many people may have a bowel movement once a day, the normal amount ranges between four times each week to several times a day.3 What differentiates infrequent stools and constipation is the consistency of the stool, the difficulty in passing it and other symptoms you may experience, such as bloating or feeling full.

Related: Natural Remedies for Constipation – With Recipes

Unfortunately, the number of people who suffer from chronic constipation is rising, leading to a characterization of the condition as a “silent epidemic” as those who suffer often suffer in silence.

Number of People Suffering From Chronic Constipation on the Rise

A recent survey by the American Gastroenterological Association4 found 16 percent of Americans suffer from chronic constipation and nearly 33 percent over age 60 experience the condition. This leads to nearly 6 million visits to the doctor’s office or clinic, and nearly 700,000 visits to an emergency room every year.5 Although the condition is normally treated on an outpatient basis, the number of people admitted to the hospital since 1997 has doubled.

One recent study estimated that if the 6 percent of Americans suffering from functional constipation incorporated natural lifestyle changes to improve their condition, $12.7 billion in direct medical costs could be avoided annually.6 The researchers felt this was a conservative estimate as it did not account for lost wages or productivity.

Related: Detox Cheap and Easy Without Fasting – Recipes Included

While the recent survey found an increasing number of people suffered from chronic constipation, it was not a study that evaluated the causes behind the problem. There are several controllable factors common to a modern lifestyle that contribute to an increasing risk, and factors over which you have no control. For instance, the number of people who suffer from constipation rises significantly with age.7 This may be related to both lifestyle choices, such as diet and exercise, and to age-related neurogenic dysfunction.8

There are a significant number of choices you make each day that increase your risk of developing chronic constipation. One is learned constipation, as your rectum is flexible and can stretch. In a study using college students, researchers found participants could easily train themselves to evacuate their bowels every 51 hours instead of every 28, leading the scientists to conclude bowel habits may induce constipation.9 Other factors that influence your risk include:10,11,12,13

Low fiber diet Changes in your routine Lack of exercise
Avoiding a bowel movement when you have the urge Drinking insufficient amount of fluid Certain medications, such as opiates, antidepressants, antacids and anti-hypertensives
Frequent use of laxatives or enemas Poor nutrition leading to vitamin deficiency, including magnesium deficiency Iron supplements

Significant Health Problems Linked to Chronic Constipation

Few people realize that chronic constipation, and the daily agony that accompanies the condition, may be dangerous or even deadly. The American College of Gastroenterology believes a diagnosis of chronic constipation warrants further medical workup, as patients may have a higher likelihood of colon cancer, even if they don’t present with colon cancer symptoms, such as GI bleeding, anemia or weight loss.14

Related: Start Eating Like That and Start Eating Like This – Your Guide to Homeostasis Through Diet

When the scientists started the study they didn’t expect too many surprises. Yet, after analyzing the results they found medical conditions they didn’t anticipate would be associated with chronic constipation, including ischemic colitis, diverticulitis and other gastrointestinal cancers.

Chronic constipation is also related to at least one brain disorder: Parkinson’s disease. A number of studies have demonstrated a link between your gut health and your psychological health. A link between an unbalanced microbiome (one symptom of which is constipation) and Parkinson’s disease may be related to proteins from the gut that accumulate in the brain. In one study, 21 days after specific proteins were injected into the stomach and intestines of mice they were found to have migrated as far as the vagus nerve.15

Constipation may also increase your risk of kidney diseases.16  Researchers reviewed medical records of over 3.5 million U.S. veterans and followed their care for seven years. At the start of the study each participant had normal kidney function. Although a causative relationship could not be proven with the method used in the study, those with constipation had a 13 percent increased risk of kidney disease and 9 percent increased risk of kidney failure.

Researchers have also found suffering from constipation may increase your risk of anal fissures, stool incontinence, hemorrhoids and urological disorders.17 The seriousness of the symptoms may vary, depending upon the severity of your constipation. An association has also been found between people suffering rectal prolapse, a condition where part of the large intestines slips out of the anus, and constipation.

Another factor connected with constipation is back pain.18 In some cases, back pain may result in the use of pain medications like opiates that slow your intestinal tract and lead to constipation. In other cases, back pain is the result of your constipation. For instance, irritable bowel syndrome or a fecal impaction may lead to back pain.

Steer Clear of Laxatives

Constipation is a symptom of other conditions and not a disease or illness process itself. Thus, treating just the symptom may mean you’re overlooking another more serious problem. Many people turn to over-the-counter laxatives to immediately relieve the discomfort, but this may have additional consequences that hinder your recovery.

Laxatives come in a variety of forms including pills, capsules, liquid, suppositories and enemas. Although tempting, if you choose to use a laxative, do it with extreme caution. The active ingredient in many enemas draw water from your body into your large intestines, softening the stool. When too much is used it can increase your risk of dehydration, and by altering your electrolyte balance, you risk kidney or heart damage and death.

Related: Hypothyroidism – Natural Remedies, Causes, and How To Heal the Thyroid

Stimulant laxatives work by increasing the muscular action in your intestines. This includes senna or cassia laxatives, often marketed as being “natural.”  Over time, these types of laxatives damage the function of your intestinal walls and decrease the ability of your muscles to contract on their own.

If you must use something to immediately relieve constipation, consider trying a glycerin suppository that doesn’t contain any stimulants. The suppository often produces results within two hours and works by drawing water into your large intestines directly where your hard stool is located, softening it enough to evacuate your bowels.

Magnesium May Help Constipation and Protect Against Disease

One of the most popular short-term natural supplements that is effective against constipation is magnesium. Magnesium is an essential mineral and a cofactor used in multiple enzymes.19 A deficiency is associated with poor absorption of vitamin D and an increased risk of heart disease, stroke, osteoporosis and diabetes. Supplementation is being used to treat migraine headaches, hypertension and asthma.

Magnesium is important to mitochondrial health, and in the production of energy in every cell in your body. It is estimated that 50 years ago people routinely received nearly 500 milligrams (mg) of magnesium every day from their food. Today, with soil depletion and poor nutritional habits, many may only receive from 100 mg to 300 mg per day. Although organic, unprocessed foods are your best bet; the amount you receive will depend upon the soil the plants were grown in.

The recommended dietary allowance (RDA) for magnesium is between 310 to 420 mg per day, dependent upon your age and sex.20However, these amounts are based on reducing your potential for deficiency and don’t necessarily address the amount you need to maintain optimal health. Some researchers believe you may need between 600 to 900 mg per day. Dr. Carolyn Dean, author of “The Magnesium Miracle,” recommends that you use your body as a marker for your ideal personal dose.

Begin by taking 200 mg of oral magnesium citrate each day and gradually increase the amount until you develop slightly loose stools. Magnesium citrate has a mild laxative effect — whatever your body doesn’t absorb will affect your intestines as it is flushed out through your stool, which helps you identify your personal cutoff point. There is ample evidence demonstrating the effectiveness of using magnesium to naturally improve constipation.21,22,23

Magnesium comes in several forms including chelate, threonate, citrate and sulfate. Citrate is the form that has the most effect on your intestinal tract and helps produce loose stools. However, if you are taking magnesium supplements for other health reasons, my personal preference is magnesium threonate as it appears to more effectively penetrate your cell membranes and boost your mitochondrial health, thus boosting your energy level.

Try Squatting to Enhance Elimination

Sitting on your toilet may be comfortable, but placement of your knees and upper legs at 90 degrees to your abdomen actually pinches off your anal canal and makes having a bowel movement more difficult. On the other hand, when you squat, your knees are brought closer to your abdomen, which changes the relationship of your rectum and sphincter, positioning your organs and muscles in a way that relaxes your rectum. This maximizes the efficiency of your evacuation.

In this position, muscles around your rectum and pubic bones relax. This encourages complete emptying of your rectum and cecum without straining. It also reduces the potential for stagnation of stool in your lower intestines and subsequent accumulation of toxins that impact the growth of your gut microbiome. In many non-Westernized cultures people routinely squat to evacuate their bowels and don’t sit on a toilet.

Related: Gluten, Candida, Leaky Gut Syndrome, and Autoimmune Diseases

It is interesting to note that in cultures where people squat daily, people don’t have the high prevalence of bowel diseases experienced in countries where toilets are commonplace. Squatting without support is challenging when you haven’t grown up squatting on a daily basis. A simple and inexpensive method of achieving good body position is to use a small foot stool. This places your organs and muscles in a more natural position and enables easier evacuation.

Fiber, Movement and Other Natural Ways of Reducing Constipation

I list several ways of reducing your risk of constipation below. But, I strongly recommend you incorporate fermented foods to help “reseed” your gut with good bacteria that will help you regain and maintain bowel regularity. The video above includes a short demonstration of how to make your own fermented foods at home. If you don’t eat fermented food, which is your best and least expensive source of probiotics, then I recommend you take a quality probiotic supplement.

In some circumstances these lifestyle choices are not enough to eliminate your constipation. As chronic constipation is one of the hallmark symptoms of hypothyroidism, it is important to discuss your situation with your physician. In many cases though, simple changes to your diet and daily lifestyle will reduce your risk of constipation and improve your gut health, such as:

Swap out processed foods for whole, high-fiber foods, such as leafy green vegetables, almonds, squash and broccoli. These foods feed your gut microbiome, reduce your vulnerability to infection and promote softer stools that keep your intestinal walls intact.24

Related: Start Eating Like That and Start Eating Like This – Your Guide to Homeostasis Through Diet

The American Heart Association recommends eating 30 grams of fiber each day,25 but the average American eats approximately 15 grams each day, which contributes to the growing rate of constipation.26
Remove gluten, artificial sweetener and sugar from your diet as they all damage your intestinal tract.
Regular exercise can also help reduce constipation.27 The physical movement helps increase the motility in your digestive tract and can stimulate the urge to have a bowel movement.
When you feel the urge to have a bowel movement, don’t wait. The longer the stool sits in your colon, the more water is removed and the more difficult it is to pass.
Consider using a foot stool to get into a squatting position to have a bowel movement. This will strengthen the muscles around your rectum and encourages a complete emptying of your bowel without straining.
Stay well hydrated with clean, pure water.
Avoid pharmaceutical drugs that change the speed of your bowel function or cause GI disruptions, such as opiate pain medications, antidepressants, antibiotics, antacids and laxatives.
Address your emotional challenges and life changes using tools, such as Emotional Freedom Techniques (EFT).

Probiotics Offer Powerful Protection Against Sepsis in Infants

Sepsis, bacteria in blood. 3D illustration showing rod-shaped bacteria in blood with red blood cells and leukocytes

(Dr. Mercola) As drug-resistant infections become more prevalent, so are cases of sepsis — a progressive disease process initiated by an aggressive, dysfunctional immune response to an infection in the bloodstream, which is why it’s sometimes referred to as blood poisoning. Unless caught and treated early, the condition can progress to septic shock, resulting in extremely low blood pressure, weakening of the heart, multiple organ failure and death.

An estimated 1 million Americans develop sepsis each year1,2 and up to 50 percent die from the systemic infection.3,4,5 While illnesses such as bronchitis, pneumonia, strep throat, kidney infection or even localized infections can turn septic, sepsis is most commonly acquired in hospital settings.6,7 Unfortunately, conventional treatment often fails, as evidenced by the 50 percent mortality rate.

It’s also costly. According to the Agency for Healthcare Research and Quality, sepsis is the most expensive condition being treated in U.S. hospitals, racking up expenses in excess of $24 billion in 2014.8 There’s good news though. Recently, evidence for not just one but two different nondrug treatments have emerged, both of which show remarkable promise.

Infants Saved by Probiotics

Sepsis can occur in just about anyone, including infants. Recent research9,10 shows feeding newborns probiotics (healthy bacteria) significantly lowers the child’s risk of developing sepsis. The study involved infants in rural India, where sepsis is common. Worldwide, an estimated 600,000 infants die from sepsis, primarily in developing countries.

The bacterial strain selected was Lactobacillus plantarum ATCC-202195 — a kind of lactic acid bacteria found in fermented vegetables such as sauerkraut and kimchi.11 To that, they added the prebiotic fructooligosaccharide “to promote growth and sustain colonization of the probiotic strain.”

The bacterial strain was chosen by methodically prescreening more than 280 strains in preliminary studies. Lactobacillus plantarum was in part chosen for its ability to attach to cells in the gut. According to NPR,12 the team was “shocked by how well the bacteria worked.” In infants given the synbiotic mix (probiotic plus prebiotic) for one week, the risk of sepsis and death dropped by 40 percent, from 9 to 5.4 percent.

A total of 149 villages in Odisha state, India — where infant mortality is the highest in the nation — were included in the study. While the team was initially planning to enroll 8,000 infants, the study was halted after the enrollment of 4,557 babies. Due to the clear evidence of significant benefit, it would have been unethical to continue depriving half of the newborns of the treatment.

Probiotic Also Lowered Other Infection Rates

The probiotic also reduced a number of other common infections. Respiratory infections, for example, were reduced by 34 percent, which was entirely unexpected. Gram-positive bacterial infections were reduced by 82 percent and gram-negative infections (which are more difficult to treat) dropped by 75 percent. Another major benefit is the price. At a cost of about $1 per infant per weeklong course of treatment, it’s incredibly affordable.

The researchers note that probiotics may be more powerful than drugs for a number of reasons. For starters, the beneficial bacteria help control harmful bacteria that may otherwise overtake the baby’s gut. The probiotic also generates compounds that strengthen the intestinal wall, thereby preventing harmful bacteria from entering the bloodstream. It also helps bolster and promote healthier maturation of the baby’s immune system.

Related Reading: Probiotics, Bacteria, and Our Health

Decline in Healthy Gut Bacteria Drives Up Disease Rates

Decades of overprescribing and misuse have made antibiotics a serious threat to human health by reducing healthy bacteria in the human microbiome and producing drug-resistant bacteria. As noted by Dr. Martin Blaser, director of the Human Microbiome Program at the NYU School of Medicine,13,14 “loss of microbes that have long accompanied humans is causing an overall rise in conditions against which our bodies can no longer defend.”

Blaser links declining gut microbes to diseases such as Type 1 diabetes, autism, inflammatory bowel diseases, food allergies and much more, noting that infancy is a critical time in which your gut microbiome is developed. The increasing use of C-sections play a role here, since this deprives the baby of exposure to the mother’s microbiome, which is picked up as the baby pushes through the birth canal.

Lack of breast-feeding adds to the problem, as breast milk helps seed the baby’s gut microbiome with healthy bacteria and indigestible sugars that feed the bacteria. Use of antibiotics during pregnancy and/or shortly after birth also disrupts the balance of bacterial communities, and recent studies suggest taking antibiotics during pregnancy increases the risk of birth defects.15

Antibiotics may also result in permanent alterations in metabolism, increasing the child’s risk of obesity later in life. Many parents are also overzealous in their use of antibacterial products, believing children must be protected against dirt and germs at all costs. This has the unfortunate side effect of weakening rather than strengthening the child’s immune system.16

Related Reading: After Taking Antibiotics, This is What You Need to Do to Restore Healthy Intestinal Flora

Getting dirty outside is actually an important part of childhood, from a health perspective, as soil-based organisms help stimulate your immune system, reduce inflammation and even aid in detoxification.

Probiotics in Wound Healing

In related news, probiotics may also lower the risk of infections during wound healing — including sepsis.17 As reported by Medical News Today:18

“Staphylococcus aureus is naturally present in the noses of around 30 percent of the population and mostly does not cause harm. However, when the skin barrier is broken, S. aureus can cause severe infection. S. aureus is notorious for forming biofilms. When this happens, the bacteria attach to a surface — such as the skin … 

Biofilms are mostly resistant to antibiotics and are therefore a considerable health risk. If S. aureus spreads to the blood it can cause sepsis, which is a major cause of death in children who have experienced severe burn injuries. Pseudomonas aeruginosa, which is another pathogen known to form biofilms, is often found in infected burn wounds …

[B]oth L. rhamnosus GG and L. reuteri could protect skin cells in the laboratory from infection by S. aureus. This was true when live bacteria were added to the skin cells and when the bacteria were killed and their extracts added instead.”

L. rhamnosus GG was found to promote cell migration, resulting in more rapid wound closure, while L. reuteri increased cell division rates, thereby aiding in the wound healing. The idea of placing live bacteria on an open wound is questionable, but since the extract of killed bacteria proved to have a similar effect, the researchers suggest bacterial extracts may eventually be used in wound care.

Vitamin C, Another Game Changer in Treatment of Sepsis

CCR17 Cure for Sepsis from Critical Care Reviews on Vimeo.

Another important medical discovery is the use of vitamin C for the treatment of sepsis. Dr. Paul Marik, chief of pulmonary and critical care medicine at Sentara Norfolk General Hospital in East Virginia, found the deadly infection could be effectively and inexpensively treated with a combination of intravenous (IV) vitamin C, thiamine (vitamin B1) and hydrocortisone (a steroid).19,20

Earlier this year, Marik published a small retrospective before-after clinical study21,22,23 showing that giving septic patients this simple IV cocktail for two days reduced mortality nearly fivefold, from 40 percent to 8.5 percent. Of the 50 patients treated, only four died, but none of them actually died from sepsis; they died from their underlying disease.

Vitamin C is well-known for its ability to prevent and treat infectious disease. Previous research has shown it effectively lowers proinflammatory cytokines and C-reactive protein.24,25,26 Influenza,27 encephalitis and measles28 have all been successfully treated with high-dose vitamin C. To investigate the mechanism of action for sepsis, Marik reached out to John Catravas, Ph.D., a pharmacology researcher at Old Dominion University.

At Marik’s request, Catravas performed an independent lab study, which confirmed the effectiveness of the treatment. Interestingly, vitamin C acts like hydrocortisone, yet when either vitamin C or the steroid was administered in isolation, nothing happened. When administered together, however, the infection was successfully eradicated.

The addition of thiamine is also important. Not only is thiamine required for metabolism of some of the metabolites of vitamin C, research has shown many patients with sepsis are vitamin deficient, and when thiamine is given, it reduces the risk of renal failure and mortality.

Nationwide Trial of Marik’s Protocol Is Underway

Sepsis kills more than breast cancer, colon cancer and AIDS combined, and Marik’s protocol has not only been shown to be profoundly effective, it has no side effects, is inexpensive, readily available and simple to administer. Patients and doctors really have nothing to lose by trying it, but to make it standard of care across the U.S., more evidence is needed.

Sentara Norfolk General Hospital, where Marik works, has already made the protocol its standard of care for sepsis, and more than 50 medical centers around the U.S. are following suit. Still, despite the successes seen in clinical practice, many doctors are wary of implementing the protocol without further studies to support it.

To test the theory on a grander scale, Dr. Craig Coopersmith, a leading sepsis researcher at Emory University School of Medicine, is now planning a multicenter trial to put Marik’s vitamin C protocol to the test across the nation. “If this is validated, this would be the single biggest breakthrough in sepsis care in my lifetime,” he told Smithsonian.29

Related Reading: Homemade Vitamin C

Results from his field trial cannot come soon enough, as current best practices are ineffective at best. For example, recent research shows the standard calling for rapid and substantial infusion of IV fluids have no effect on survival rates,30 and previous guidelines calling for the use of a specific drug turned out to do more harm than good.31 In short, there are few good alternatives available, making Marik’s treatment protocol all the more crucial.

Are You at High Risk for Sepsis?

With sepsis affecting more than a million Americans each year, it’s important to be aware of its signs, symptoms and risks.32 Even health care workers can miss the signs and delay treatment. According to the Centers for Disease Control and Prevention (CDC), you’re at higher risk for sepsis if you have:

  • Chronic disease. A vast majority — 7 out of 10 — of people who develop sepsis have some kind of chronic health condition. Those with diabetes, lung, kidney or liver disease tend to be particularly susceptible to infection, which raises the risk.
  • Weakened immune system, AIDS or cancer.
  • Recently spent time in a hospital, nursing home or other health care facility, as exposure to infection-causing bacteria is common in these places.

Common Sense Strategies to Reduce Your Risk of Sepsis

While health care workers have a responsibility to prevent infections that could potentially turn septic and to educate patients about warning signs of sepsis, you can lower your own risk by:

•Promptly treating urinary tract infections (UTIs). UTIs are the second most common type of infection in the body, sending more than 8 million people to their health care providers every year in the U.S. alone,33 and one-quarter of sepsis cases are related to urinary tract infections.

Conventional treatment typically involves antibiotics, but research shows 90 percent of UTIs can be successfully treated with D-Mannose, a naturally occurring sugar that’s closely related to glucose. To learn more, see “D-Mannose for UTI Prevention Validated in a Clinical Trial.”

•Properly clean skin wounds. About 1 in 10 sepsis cases are due to skin infections, so always take the time to properly clean and care for wounds and scrapes. Wash the wound with mild soap and water to clean out dirt and debris, then cover with a sterile bandage. Diabetics should follow good foot care to avoid dangerous foot infections.

•Avoid infections in hospitals. When visiting a health care facility, be sure to wash your own hands, and remind doctors and nurses to wash theirs (and/or change gloves) before touching you or any equipment being used on you.

If you have to undergo a colonoscopy or other testing using a flexible medical scope, remember to call and ask how they clean their scopes and what kind of cleaning solution they use. If the answer is glutaraldehyde (brand name Cidex), find another hospital or clinic — one that uses peracetic acid. This preliminary legwork will significantly decrease your risk of contracting an infection from a contaminated scope.

Sources:

How to Grow Dandelion Greens

(Dr. Mercola) Dandelion greens are nutritious, delicious and versatile. They can be added to salads, soups and stews or sautéed and served as a side dish. What you may have only thought of as a pesky weed in your yard is actually a flowering herb with significant health benefits.

The dandelion plant belongs to the largest plant family — the Asteraceae or sunflower family — which includes more than 22,000 species, such as daisies and thistles. The dandelion alone has more than 100 different species, all of which are beneficial to your health.1 In fact, every part of the dandelion can be used, from the roots to the leaves and flowers.

You probably know how difficult they are to eradicate from your yard. When you mow them each week, the plant accommodates and grows a shorter stalk.2 Dandelions have become masters of survival, which is likely what makes them such successful weeds. However, while you may not want them growing in your yard, there are benefits to growing your own patch of dandelions and harvesting the greens for your table.

History of the Dandelion Herb

The dandelion has been embraced across cultures and centuries, but has now been branded suburban enemy No 1. An estimated 80 million pounds of chemicals are poured on yards across the U.S. to eradicate the little flowering herbs, but year after year these hardy plants return. Before the invention of lawns, however, gardeners used to weed out the grass to make room for more dandelions.

The name of the plant originated from the French who called it “dent de lion” or tooth of the lion, as the jagged edges of the leaves are suggestive of a lion’s tooth.3 Although it is native to Europe and Asia, it has been carried around the world and is probably one of the most recognizable plants worldwide. It is believed the European settlers found the plant so useful they purposefully brought the dandelion with them to the New World.

The official botanical name for the dandelion is Taraxacum officinale. The pollen from the dandelion doesn’t cause allergic reactions as the grains are too large. However, the sap from the plant may cause a common contact dermatitis resulting in swelling and itching.4

The plant is known to grow just about anywhere, but loves direct sunlight. As the flower matures it forms a familiar white puff of seeds that can float as far as 100 miles in the wind before settling into the soil and seeding yet another plot of land.5 Some outdoorsmen claim the dandelion helps them predict the weather. After the flower has gone to seed, if rain is coming the head reportedly will cover the seeds to protect the seed ball until the threat of rain has passed.6

Related: Five Common Weeds to Cultivate for Health and Nutrition

Plant Your Dandelion Crop in the Spring

If you are planting your own dandelion crop, it is probably best to plant them furthest from your neighbor’s yard and remove the heads before they seed. You can grow a full crop in your backyard using an inexpensive hot house that allows sun in and keeps the seeds from spreading. Even with such precautions, seed can still leave the hothouse on your clothing or on the sole of you shoes, so you’ll still want to remove the heads before the seed ball forms.

When you are starting a crop, the first seeds can be sown outside approximately four to six weeks before the last frost.7 Once they have sprouted, which takes seven to 10 days,8 you’ll want to thin them so they are 6 to 8 inches apart, allowing for full growth of the greens and plenty of room for the tap root. You can choose from a variety of different dandelion plants to meet your particular needs. The Clio produces upright greens that are easy to harvest and the Ameliore is a French strain with broader leaves and a milder flavor.9

The root of the dandelion routinely goes 18 inches deep into the soil and is an excellent way of keeping the soil from compacting.10 The root is sturdy and often has little hairy rootlets that may remain in the ground when you harvest your plants and regrow a new plant.11Although the plants are incredibly resilient to poor conditions, the quality of nutrition you receive from the greens will depend on the quality of the soil the herb grows in.

Dandelions thrive in full sun, but will grow in partial shade. Use soil that drains well and compost the soil in the fall to encourage a strong spring crop. You can harvest the leaves and flowers throughout the summer months. The roots are best harvested during frost-free fall months.12 Before harvesting the leaves, cover the plants with a dark opaque cloth so the leaves blanch, reducing the bitterness of the greens.13

The blossoms should be harvested when they are young and tender, just as they have bloomed. Putting them in a bowl of cold water will prevent them from closing before you eat them.14

Dandelions will grow problem free. You won’t have to treat for pests or change planting location unless they are planted in full shade. Dandelions may also be grown in container gardens, which makes covering them to blanch the leaves, or cutting the flower when they go to seed, much easier than if they are planted in your herb garden. Containers can also be set up high to reduce the potential for back pain as you are bending to care for the plants and prevent them from seeding your lawn or your neighbor’s yard.

Related: Dandelions

Dandelions Have Significant Health Benefits

Small birds eat the seeds of the dandelion; pigs, goats and rabbits eat the flowers and the nectar is food for the honey bee.15 But, beyond a food source for wildlife, the dandelion holds an amazing amount of health benefits for you as well. There are uses in your kitchen from the root to the flower, and health benefits to each part of the plant as well. Some studies have demonstrated the greens help produce antibodies to cancer.16

Dandelion greens are high in calcium, iron and potassium.17 They are also rich in vitamins C, A, K,18 thiamine and riboflavin,19 and surprisingly rank ahead of both broccoli and spinach in nutritional value. A full cup of chopped greens is a low 24 calories, packing more nutrition in a serving than some of the vegetables you routinely grow in your garden each year.

The vitamins and minerals provided in your dandelion greens help prevent Alzheimer’s disease, eye disorders, support your immune system and the development of strong bones and teeth. Practitioners of folk medicine have been using dandelion root and leaves for centuries to prevent and treat several health conditions. The root of the plant increases the flow of bile that may help reduce gallstones, liver congestion and inflammation and jaundice.20

The plant has a second name, “pis-en-lit,” (wet the bed) — a name that refers to the diuretic effect of its greens.21 When eaten before bed, they may require you make several trips to the bathroom during the night. Some find the leaves to have a mild laxative effect that aids in movement through your digestive tract.22 Traditionally, the root of the dandelion has been used in the treatment of rheumatism, as it has mild anti-inflammatory effects.

Time of harvest affects the properties of the root. Fall harvest has the greatest health benefits and produces an opaque extract with higher levels of inulin and levulin, starch-like substances that may help balance your blood sugar.23 Spring and summer harvest of the root produces a less bitter product, but with less potent health benefits.

The herb has been used by Native Americans to help heartburn and upset stomach and the Chinese have used it to improve breast milk flow and reduce inflammation in the breast during lactation.24 The Europeans used dandelion greens to help relieve fever, boils, diarrhea and diabetes. As a precautionary note, dandelions may make the side effects of lithium worse, and may increase your risk of bleeding if you are taking a blood thinner.25

Related: 80% Raw Food Diet

Dandelions Propagate Profusely

Dandelions growing in the center of your yard can be harvested and eaten as long as your yard is chemical free and your neighbors don’t spray. Even if your neighbors use chemical pellets to treat the yard, the chemicals migrate to the edges of your yard, so don’t harvest and eat the dandelions within 10 feet of your neighbor’s yard.

You may end up with dandelions in your own yard in places where you don’t want them growing. There are several ways to remove them without resorting to chemicals. Even the pellets you sprinkle across your lawn to control weeds contribute to the damage done to wildlife in your area and groundwater pollution that affects the quality of drinking water. Over 5 billion pounds of pesticides are used annually across the world.26 These chemicals affect both plant life and the birds and wildlife that feed on the vegetation.

In most instances the chemicals are fat soluble. This means there is significant biomagnification as the chemicals remain in the insect and animal bodies and accumulate up the food chain. A conservative estimate is that 672 million birds are exposed to pesticides in the U.S. annually and 10 percent of those, or 67 million, are killed outright from ingesting the chemicals.27 The extent of the damage done long term to the bird population is difficult to estimate.

Birds exposed to chemicals also suffer “sublethal” effects that include thinning egg shells that break under the weight of the incubating adult, hormone disruption, impaired immune systems and a lack of appetite.28 Each of these consequences severely impairs the ability of the bird to reproduce, migrate and survive.

Related: Repel Mosquitoes by Cultivating Marigolds

Birds may be particularly vulnerable as they can both mistake the pesticide pellets for seed and eat insects that are also laden with chemicals, doubling the load of pesticides they ingest.

Children are also more vulnerable than adults as they absorb more chemicals for their size relative to adults and are more vulnerable to the effects of the toxins in their bodies. A report by Environmental and Human Health Inc. found children exposed to pesticides had a higher incidence of childhood leukemia, soft tissue sarcomas and brain cancers.29

Related: Diatomaceous Earth – Mother Nature’s Secret Weapon: What Is It, How to Use It, Where to Find It

Some assume these chemicals are safe for use as they are sold over-the-counter, but while the Environmental Protection Agency classifies four of the more common lawn chemicals as having insufficient data to assess the impact on the development of cancer in humans, all are associated with the sixth most common form of cancer in the U.S., non-Hodgkin lymphoma.30

These chemicals don’t disappear after a couple of days either. They are incorporated into the leaves of the grass eaten by insects and your pet dog. They seep into the groundwater in your neighborhood, which affects the water that eventually reaches your tap. Residue is tracked indoors on the bottom of your shoes where it accumulates in the dust in your home.

Get Rid of Your Lawn Dandelions Naturally

There are several ways to keep your lawn clear of dandelions without resorting to toxic chemicals. Dandelions thrive in direct sunlight so when the grass grows 3 to 4 inches tall it helps to reduce the growth of the plant. The plant won’t flower until all the leaves have formed and only if there is sufficient sunlight and moisture.31 In the short time-lapsed video above you can watch one dandelion go from flower to seed ball in two days.

Related: How to Test and Amend Soil

You can kill the plant, and therefore not worry about the tap root producing another plant, by spraying a mixture of white vinegar, water and salt directly on the plant. This will kill the surrounding plants as well, so use a direct spray and be careful where you aim it.

Your third option is to pull the plants from the ground, being careful to pull up the tap root from the end as any root you leave will produce another plant. Work in your yard when the ground is moist, such as after a deep watering or a long slow rain. Mother Earth News recommends three different weeders designed specifically for dandelions to help you remain chemical free.32

Each of the weeding options allow you to work standing up to reduce strain on your lower back and knees. The prices range between $20 and $30. Using a combination of all three strategies — length of grass, spraying individual plants with vinegar and salt and pulling individual plants — may help you keep a lawn free of dandelions and even address other types of weeds. Remember to address the plant before it goes to seed, as once the seeds begin to spread, all control is lost.

Use the Leaves, Roots and Flowers in Recipes at Home

In this short video, a chef from the Martha Steward test kitchen demonstrates making a chick pea and dandelion salad using fresh from the garden vegetables. Using the greens in a salad is just one way to use the plant — there are many more:33,34

Related: Three Easy Mushroom Varieties To Grow at Home
Roots can be dried, ground and brewed like coffee Dandelion wine made from the flowers Flowers fried in butter
Dry the roots, roast a 300 degrees F and grind; add to hot chocolate Mix greens in potato salad or egg salad Sautéed like spinach and added to eggs, served as a side dish or in a quiche
Cold pickling in a salt brine; heat may destroy the delicate leaves Kimchi made with dandelion greens Flowers mixed with apple peel or orange zest and made into jam
Roots chopped fine and stir fried Dandelion pumpkin seed pesto Dandelion blossom cookies
Recommended Reading:

Aspartame Tied to Weight Gain, Increased Appetite, Obesity

(U.S. Right To Know) Aspartame, the world’s most popular sugar substitute, is found in thousands of sugar-free, low-sugar and so-called “diet” drinks and foods. Yet the scientific evidence described in this fact sheet links aspartame to weight gain, increased appetite, diabetes, metabolic derangement and obesity-related diseases.

Please share this resource. See also our companion fact sheet, Aspartame: Decades of Science Point to Serious Health Risks, with information about the peer-reviewed studies linking aspartame to cancer, cardiovascular disease, Alzheimer’s disease, strokes, seizures, shortened pregnancies and headaches.

Recommended Reading: Healthy Sugar Alternatives & More

Quick Facts

  • Aspartame — also marketed as NutraSweet, Equal, Sugar Twin and AminoSweet — is the world’s most widely used artificial sweetener. The chemical is found in thousands of food and beverageproducts, including Diet Coke and Diet Pepsi, sugar-free gum, candy, condiments and vitamins.
  • The FDA has said aspartame is “safe for the general population under certain conditions.” Many scientists have said the FDA approval was based on suspect data and should be reconsidered.
  • Dozens of studies conducted over decades link aspartame to serious health problems.

Aspartame, Weight Gain + Obesity Related Issues 

Five reviews of the scientific literature on artificial sweeteners suggest that they do not contribute to weight loss, and instead may cause weight gain.

  • A 2017 meta analysis of research on artificial sweeteners, published in the Canadian Medical Association Journal, found no clear evidence of weight loss benefits for artificial sweeteners in randomized clinical trials, and reported that cohort studies associate artificial sweeteners with “increases in weight and waist circumference, and higher incidence of obesity, hypertension, metabolic syndrome, type 2 diabetes and cardiovascular events.”1
    • See also: “Artificial sweeteners don’t help with weight loss and may lead to gained pounds,” by Catherine Caruso, STAT (7.17.2017)
  • A 2013 Trends in Endocrinology and Metabolism review article finds “accumulating evidence suggests that frequent consumers of these sugar substitutes may also be at increased risk of excessive weight gain, metabolic syndrome, type 2 diabetes, and cardiovascular disease,” and that “frequent consumption of high-intensity sweeteners may have the counterintuitive effect of inducing metabolic derangements.”2
  • A 2009 American Journal of Clinical Nutrition review article finds that the “addition of NNS [nonnutritive sweeteners] to diets poses no benefit for weight loss or reduced weight gain without energy restriction. There are long-standing and recent concerns that inclusion of NNS in the diet promotes energy intake and contributes to obesity.”3
  • A 2010 Yale Journal of Biology and Medicine review of the literature on artificial sweeteners concludes that, “research studies suggest that artificial sweeteners may contribute to weight gain.”4
  • A 2010 International Journal of Pediatric Obesity review article states, “Data from large, epidemiologic studies support the existence of an association between artificially-sweetened beverage consumption and weight gain in children.”5
Recommended Reading: Diet Soda, Aspartame Linked to Premature Deaths in Women

Epidemiological evidence suggests that artificial sweeteners are implicated in weight gain. For example:

  • The San Antonio Heart Study “observed a classic, positive dose-response relationship between AS [artificially sweetened] beverage consumption and long-term weight gain.” Furthermore, it found that consuming more than 21 artificially sweetened beverages per week – compared to those who consumed none, “was associated with almost-doubled risk” of overweight or obesity.”6
  • A study of beverage consumption among children and adolescents aged 6-19 published in International Journal of Food Sciences and Nutrition found that “BMI is positively associated with consumption of diet carbonated beverages.”7
  • A two-year study in of 164 children published in the Journal of the American College of Nutrition found that “Increases in diet soda consumption were significantly greater for overweight and subjects who gained weight as compared to normal weight subjects. Baseline BMI Z-score and year 2 diet soda consumption predicted 83.1% of the variance in year 2 BMI Z-score.” It also found that “Diet soda consumption was the only type of beverage associated with year 2 BMI Z-score, and consumption was greater in overweight subjects and subjects who gained weight as compared to normal weight subjects at two years.”8
  • The U.S. Growing Up Today study of more than 10,000 children aged 9-14 found that, for boys, intakes of diet soda “were significantly associated with weight gains.”9
  • A 2016 study in the International Journal of Obesity reported finding seven tentatively replicated factors showing significant associations with abdominal obesity in women, including aspartame intake.10
  • People who regularly consume artificial sweeteners are at increased risk of “excessive weight gain, metabolic syndrome, type 2 diabetes, and cardiovascular disease,”11 according to a 2013 Purdue review over 40 years published in Trends in Endocrinology & Metabolism

Other types of studies similarly suggest that artificial sweeteners do not contribute to weight loss. For example, interventional studies do not support the notion that artificial sweeteners produce weight loss. According to the Yale Journal of Biology and Medicine review of the scientific literature, “consensus from interventional studies suggests that artificial sweeteners do not help reduce weight when used alone.”12

Some studies also suggest that artificial sweeteners increase appetite, which may promote weight gain. For example, the Yale Journal of Biology and Medicine review found that “Preload experiments generally have found that sweet taste, whether delivered by sugar or artificial sweeteners, enhanced human appetite.”13

Studies based on rodents suggest that consumption of artificial sweeteners can lead to consuming extra food. According to the Yale Journal of Biology and Medicine review, “ Inconsistent coupling between sweet taste and caloric content can lead to compensatory overeating and positive energy balance.” In addition, according to the same article, “artificial sweeteners, precisely because they are sweet, encourage sugar craving and sugar dependence.”14

Recommended Reading: Why You Should Avoid High Fructose Corn Syrup & Aspartame

A 2014 study in the American Journal of Public Health found that “Overweight and obese adults in the United States drink more diet beverages than healthy-weight adults, consume significantly more calories from solid food—at both meals and snacks—than overweight and obese adults who drink SSBs [sugar-sweetened beverages], and consume a comparable amount of total calories as overweight and obese adults who drink SSBs.”15

A 2015 study of older adults in the Journal of the American Geriatrics Society found “In a striking dose-response relationship,” that “increasing DSI [diet soda intake] was associated with escalating abdominal obesity…”16

An important 2014 study published in Nature found that “consumption of commonly used NAS [non-caloric artificial sweetener] formulations drives the development of glucose intolerance through induction of compositional and functional alterations to the intestinal microbiota … our results link NAS consumption, dysbiosis and metabolic abnormalities … Our findings suggest that NAS may have directly contributed to enhancing the exact epidemic that they themselves were intended to fight.”17

Diabetes and Metabolic Derangement

Aspartame breaks down in part into phenylalanine, which interferes with the action of an enzyme intestinal alkaline phosphatase (IAP) previously shown to prevent metabolic syndrome, which is a group of symptoms associated with type 2 diabetes and cardiovascular disease. According to a 2017 study in Applied Physiology, Nutrition and Metabolism, mice receiving aspartame in their drinking water gained more weight and developed other symptoms of metabolic syndrome than animals fed similar diets lacking aspartame. The study concludes, “IAP’s protective effects in regard to the metabolic syndrome may be inhibited by phenylalanine, a metabolite of aspartame, perhaps explaining the lack of expected weight loss and metabolic improvements associated with diet drinks.”18

  • See also: Mass General press release on the study, “Aspartame may prevent, not promote, weight loss by blocking intestinal enzyme’s activity”

People who regularly consume artificial sweeteners are at increased risk of “excessive weight gain, metabolic syndrome, type 2 diabetes, and cardiovascular disease,” according to a 2013 Purdue review over 40 years published in Trends in Endocrinology & Metabolism.19

In a study that followed 66,118 women over 14 years, both sugar sweetened beverages and artificially sweetened beverages were associated with risk of Type 2 diabetes. “Strong positive trends in T2D risk were also observed across quartiles of consumption for both types of beverage … No association was observed for 100% fruit juice consumption,” reported the 2013 study published in American Journal of Clinical Nutrition.20

Recommended Reading: Foods That Feed Candida

Intestinal Dysbiosis, Metabolic Derangement and Obesity

Artificial sweeteners can induce glucose intolerance by altering the gut microbiota, according to a 2014 study in Nature. The researchers wrote, “our results link NAS [non-caloric artificial sweetener] consumption, dysbiosis and metabolic abnormalities, thereby calling for a reassessment of massive NAS usage … Our findings suggest that NAS may have directly contributed to enhancing the exact epidemic [obesity] that they themselves were intended to fight.”21

A 2016 study in Applied Physiology Nutrition and Metabolism reported, “Aspartame intake significantly influenced the association between body mass index (BMI) and glucose tolerance… consumption of aspartame is associated with greater obesity-related impairments in glucose tolerance.”22

According to a 2014 rat study in PLoS ONE, “aspartame elevated fasting glucose levels and an insulin tolerance test showed aspartame to impair insulin-stimulated glucose disposal … Fecal analysis of gut bacterial composition showed aspartame to increase total bacteria…”23

Industry Science

Not all recent studies find a link between artificial sweeteners and weight gain. Two industry-funded studies did not.

  • A 2014 American Journal of Clinical Nutrition meta-analysis concluded that “Findings from observational studies showed no association between LCS [low-calorie sweetener] intake and body weight or fat mass and a small positive association with BMI [body mass index]; however, data from RCTs [randomized controlled trials], which provide the highest quality of evidence for examining the potentially causal effects of LCS intake, indicate that substituting LCS options for their regular-calorie versions results in a modest weight loss and may be a useful dietary tool to improve compliance with weight loss or weight maintenance plans.” The authors “received funding to conduct this research from the North American Branch of the International Life Sciences Institute (ILSI).”24

According to a 2010 article in Nature, ILSI is “largely funded by food, chemical and pharmaceutical companies.”25 See also US Right to Know fact sheet: ILSI Wields Stealthy Influence for Food and Agrichemical Industries.

A series of stories published in UPI in 1987 by investigative reporter Greg Gordon describe ILSI’s involvement in directing research on aspartame toward studies likely to support the sweetener’s safety.

  • A 2014 study in the journal Obesity tested water against artificially sweetened beverages for a 12-week weight loss program, finding that “water is not superior to NNS [non-nutritive sweetened] beverages for weight loss during a comprehensive behavioral weight loss program.” The study was “fully funded by the American Beverage Association,”26 which is the main lobbying group for the soda industry.

There is strong evidence that industry-funded studies in biomedical research are less trustworthy than those funded independently. A 2007 PLOS Medicine study on industry support for biomedical research found that “Industry funding of nutrition-related scientific articles may bias conclusions in favor of sponsors’ products, with potentially significant implications for public health … scientific articles about commonly consumed beverages funded entirely by industry were approximately four to eight times more likely to be favorable to the financial interests of the sponsors than articles without industry-related funding. Of particular interest, none of the interventional studies with all industry support had an unfavorable conclusion…”27

Recommended Reading: Are You Buying Stevia or Something Else?

Is “Diet” Deceptive Marketing?

In April 2015, US Right to Know petitioned the Federal Trade Commission (FTC) and the Food and Drug Administration (FDA) to investigate the marketing and advertising practices of “diet” products that contain a chemical linked to weight gain.

We argued that the term “diet” appears to be deceptive, false and misleading in violation of section 5 of the Federal Trade Commission Act and section 403 of the Federal Food, Drug and Cosmetic Act. The agencies have so far declined to act citing lack of resources and other priorities (see FDA and FTC responses).

“It’s regrettable that the FTC won’t act to halt the deceptions of the ‘diet’ soda industry. Ample scientific evidence links artificial sweeteners to weight gain, not weight loss,” said Gary Ruskin, co-director of U.S. Right to Know. “I do believe that ‘diet’ soda will go down in U.S. history as one of the greatest consumer frauds ever.”

News coverage:

USRTK press releases and posts:

Related Reading:

 

Sources:

[1] Azad, Meghan B., et al. Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies. CMAJ July 17, 2017 vol. 189 no. 28 doi: 10.1503/cmaj.161390 (abstract / article)

[2] Swithers SE, “Artificial Sweeteners Produce the Counterintuitive Effect of Inducing Metabolic Derangements.” Trends in Endocrinology and Metabolism, July 10, 2013. 2013 Sep;24(9):431-41. PMID: 23850261. (abstract / article)

[3] Mattes RD, Popkin BM, “Nonnutritive Sweetener Consumption in Humans: Effects on Appetite and Food Intake and Their Putative Mechanisms.” American Journal of Clinical Nutrition, December 3, 2008. 2009 Jan;89(1):1-14. PMID: 19056571. (article)

[4] Yang Q, “Gain Weight by ‘Going Diet?’ Artificial Sweeteners and the Neurobiology of Sugar Cravings.” Yale Journal of Biology and Medicine, 2010 Jun;83(2):101-8. PMID: 20589192. (article)

[5] Brown RJ, de Banate MA, Rother KI, “Artificial Sweeteners: a Systematic Review of Metabolic Effects in Youth.” International Journal of Pediatric Obesity, 2010 Aug;5(4):305-12. PMID: 20078374. (abstract / article)

[6] Fowler SP, Williams K, Resendez RG, Hunt KJ, Hazuda HP, Stern MP. “Fueling the Obesity Epidemic? Artificially Sweetened Beverage Use and Long-Term Weight Gain.” Obesity, 2008 Aug;16(8):1894-900. PMID: 18535548. (abstract / article)

[7] Forshee RA, Storey ML, “Total Beverage Consumption and Beverage Choices Among Children and Adolescents.” International Journal of Food Sciences and Nutrition. 2003 Jul;54(4):297-307. PMID: 12850891. (abstract)

[8] Blum JW, Jacobsen DJ, Donnelly JE, “Beverage Consumption Patterns in Elementary School Aged Children Across a Two-Year Period.” Journal of the American College of Nutrition, 2005 Apr;24(2):93- 8. PMID: 15798075. (abstract)

[9] Berkey CS, Rockett HR, Field AE, Gillman MW, Colditz GA. “Sugar-Added Beverages and Adolescent Weight Change.”Obes Res. 2004 May;12(5):778-88. PMID: 15166298. (abstract / article)

[10] W Wulaningsih, M Van Hemelrijck, K K Tsilidis, I Tzoulaki, C Patel and S Rohrmann. “Investigating nutrition and lifestyle factors as determinants of abdominal obesity: an environment-wide study.” International Journal of Obesity (2017) 41, 340–347; doi:10.1038/ijo.2016.203; published online 6 December 2016 (abstract / article)

[11] Susan E. Swithers, “Artificial sweeteners produce the counterintuitive effect of inducing metabolic derangements.” Trends Endocrinol Metab. 2013 Sep; 24(9): 431–441.

[12] Yang Q, “Gain Weight by ‘Going Diet?’ Artificial Sweeteners and the Neurobiology of Sugar Cravings.” Yale Journal of Biology and Medicine, 2010 Jun;83(2):101-8. PMID: 20589192. (article)

[13] Yang Q, “Gain Weight by ‘Going Diet?’ Artificial Sweeteners and the Neurobiology of Sugar Cravings.” Yale Journal of Biology and Medicine, 2010 Jun;83(2):101-8. PMID: 20589192. (article)

[14] Yang Q, “Gain Weight by ‘Going Diet?’ Artificial Sweeteners and the Neurobiology of Sugar Cravings.” Yale Journal of Biology and Medicine, 2010 Jun;83(2):101-8. PMID: 20589192. (article)

[15] Bleich SN, Wolfson JA, Vine S, Wang YC, “Diet-Beverage Consumption and Caloric Intake Among US Adults, Overall and by Body Weight.” American Journal of Public Health, January 16, 2014. 2014 Mar;104(3):e72-8. PMID: 24432876. (abstract / article)

[16] Fowler S, Williams K, Hazuda H, “Diet Soda Intake Is Associated with Long-Term Increases in Waist Circumference in a Biethnic Cohort of Older Adults: The San Antonio Longitudinal Study of Aging.” Journal of the American Geriatrics Society, March 17, 2015. (abstract / article)

[17] Suez J. et al., “Artificial Sweeteners Induce Glucose Intolerance by Altering the Gut Microbiota.” Nature, September 17, 2014. 2014 Oct 9;514(7521):181-6. PMID: 25231862 (abstract)

[18] Gul SS, Hamilton AR, Munoz AR, Phupitakphol T, Liu W, Hyoju SK, Economopoulos KP, Morrison S, Hu D, Zhang W, Gharedaghi MH, Huo H, Hamarneh SR, Hodin RA. “Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice.” Appl Physiol Nutr Metab. 2017 Jan;42(1):77-83. doi: 10.1139/apnm-2016-0346. Epub 2016 Nov 18. (abstract / article)

[19] Susan E. Swithers, “Artificial sweeteners produce the counterintuitive effect of inducing metabolic derangements.” Trends Endocrinol Metab. 2013 Sep; 24(9): 431–441. (article)

[20] Guy Fagherazzi, A Vilier, D Saes Sartorelli, M Lajous, B Balkau, F Clavel-Chapelon. “Consumption of artificially and sugar-sweetened beverages and incident type 2 diabetes in the Etude Epidémiologique auprès des femmes de la Mutuelle Générale de l’Education Nationale–European Prospective Investigation into Cancer and Nutrition cohort.” Am J Clin Nutr. 2013, Jan 30; doi: 10.3945/ ajcn.112.050997 ajcn.050997. (abstract/article)

[21] Suez J et al. “Artificial sweeteners induce glucose intolerance by altering the gut microbiota.” Nature. 2014 Oct 9;514(7521). PMID: 25231862. (abstract / article)

[22] Kuk JL, Brown RE. “Aspartame intake is associated with greater glucose intolerance in individuals with obesity.” Appl Physiol Nutr Metab. 2016 Jul;41(7):795-8. doi: 10.1139/apnm-2015-0675. Epub 2016 May 24. (abstract)

[23] Palmnäs MSA, Cowan TE, Bomhof MR, Su J, Reimer RA, Vogel HJ, et al. (2014) Low-Dose Aspartame Consumption Differentially Affects Gut Microbiota-Host Metabolic Interactions in the Diet-Induced Obese Rat. PLoS ONE 9(10): e109841. (article)

[24] Miller PE, Perez V, “Low-Calorie Sweeteners and Body Weight and Composition: a Meta-Analysis of Randomized Controlled Trials and Prospective Cohort Studies.” American Journal of Clinical Nutrition, June 18, 2014. 2014 Sep;100(3):765-77. PMID: 24944060. (abstract / article)

[25] Declan Butler, “Food Agency Denies Conflict-of-Interest Claim.” Nature, October 5, 2010. (article)

[26] Peters JC et al., “The Effects of Water and Non-Nutritive Sweetened Beverages on Weight Loss During a 12-Week Weight Loss Treatment Program.” Obesity, 2014 Jun;22(6):1415-21. PMID: 24862170. (abstract / article)

[27] Lesser LI, Ebbeling CB, Goozner M, Wypij D, Ludwig DS. “Relationship Between Funding Source and Conclusion Among Nutrition-Related Scientific Articles.” PLOS Medicine, 2007 Jan;4(1):e5. PMID: 17214504. (abstract / article)

How to Help Heal Mental Disorders With Nutrition

(Dr. Mercola) Can you use specific nutrients to improve your mental health? Yes, you can. William Walsh, Ph.D., president of the nonprofit Walsh Research Institute in Naperville, Illinois, and author of “Nutrient Power: Heal Your Biochemistry and Heal Your Brain,” specializes in nutrient-based psychiatry and nutritional medicine.

He and I are both  fellows of the American College of Nutrition. He’s designed nutritional programs for Olympic athletes, NBA players and major league baseball players. More importantly, he’s spent a great deal of his career seeking to improve mental health through nutrition.

“I started off in the hard science. I was an experimentalist,” Walsh says. “I worked, in the beginning, in the nuclear field … with places like Los Alamos, the Institute for Atomic Research and University of Michigan Research Institute. I wound up at Argonne National Laboratory. While working as a scientist there, I started a volunteer project at the local prison, Stateville Penitentiary.

I eventually got really interested in why people were violent …  [W]hen we started the ex-offender program, I got to meet the families that had produced a criminal. I found some wonderful families, caring and capable families, that have other children who turned out just fine …

I began to realize we didn’t understand why people had bad behavior. We then asked the question, ‘Could it be something related to their brain chemistry or the body chemistry?’… I started doing lab studies of their blood, their urine and hair. I found out that they were very, very different from the rest of the population. That’s how I got started.”

Biochemistry and the Criminal Brain

Walsh received valuable direction after meeting Dr. Carl Pfeiffer, who was doing work on heavy metals and schizophrenia. As it turns out, levels of metals, including copper, zinc and manganese, were all abnormal in criminals compared to the general population.

Walsh discovered four biochemical types of violent people. One of these was the sociopaths, all of whom had severe zinc deficiency, pyrrole disorder, low blood spermine and undermethylation. In all, it’s an unusual combination of bad biochemistry. A collaborative investigation with Pfeiffer resulted in nutrient therapies for each of the behavior types.

Pyrrole disorder is a stress condition commonly found in brain disorders. A urine test developed by niacin expert Abram Hoffer and Pfeiffer is the gold standard test for this genetic condition, which involves altered  biochemistry in your bone marrow and spleen.

People who have pyrrole disorder may produce five to 10 times more pyrroles than normal — a byproduct of natural reactions, like the formation of hemoglobin. While harmless in and of itself, pyrroles bind to and draw out anything that is an aldehyde, such as B-6. It also sharply depletes zinc.

As a result, people with pyrroles disorder have exceptionally low levels of B-6, and zinc which can have serious effects on brain function, affecting their memory and ability to read, for example. B-6 deficiency is quite common among children with attention deficit hyperactivity disorder (ADHD) as well.

Related: Increase your IQ with the Right Foods, Herbs, Vitamins

The Earlier the Treatment the Better the Results

“Eventually, [Pfeiffer] and I jointly evaluated 500 patients, mostly violent adults and violent children. We got our best results with the kids, young people with the same kind of chemistry, who were mostly very violent,” Walsh says.

“I have to say we didn’t really succeed in finding a way to help the adult criminals. They would get better for six to eight months, and then I’d find out they were back in prison. That had a lot to do with the fact that they were abusing alcohol and illegal drugs … At about 1990, we decided to focus on children …

It’s been very successful. If we can get a child before their lives are ruined, before they pass puberty perhaps, our success rate [is] very high … The doctors report a striking improvement in behavior. Most of these kids, of course, [are] on drugs, everything from Ritalin to powerful antipsychotic  medications. Usually when we’re finished and [have] balanced their chemistry, they can wean off the medication. They usually are fine without it …”

Nutrients Involved in Synthesis or Functioning of Neurotransmitters Dictate Mental Function

Later on, Walsh expanded to also include children with autism and ADHD. Fond of numbers, Walsh began amassing enormous databases. At present, he has one of the world’s largest chemistry database for autism, depression and behavior disorders.

“When you look at these millions of chemical analyses of blood, urine and tissues, it’s obvious that there are very great differences,” he says. “I found that for mental disorders, about six or seven chemical imbalances dominate mental function. There are hundreds and hundreds of important nutrients in the body, but in the brain, there are about six or seven that [seem] to dominate everything. Eventually, I found out why …

[T]hese are the nutrient factors that are either involved in synthesis of a neurotransmitter or the functioning of a neurotransmitter. They include methylation — undermethylation or overmethylation. In our database, 70 percent of all humans in the United States have normal, typical methylation; 22 percent are undermethylated … 8 percent are overmethylated.

About 70 percent of all people who have a mental disorder have one of these methylation disorders. The symptoms are completely different, and the treatment they need is completely different. We also found that most people [who have mental disorders] are depleted or deficient in zinc. That’s the most common [deficiency] we see … Virtually everyone with a mental disorder seems to need zinc and improve on it.”

Copper Overload Linked to Autism, Schizophrenia and Postpartum Depression

Copper is another important trace metal, as it plays a distinct role in the synthesis of norepinephrine, a major neurotransmitter. Divalent copper (Cu2+) is a dramatic factor in the ratio of dopamine and norepinephrine.

Related: Autism, Gut Health, Obesity, the MMR Vaccine, and Andrew Wakefield

Animal studies have shown that when animals are starved of copper until they only have 25 percent of the normal amount of copper in their blood, the ratio between norepinephrine and dopamine is changed by more than a factor of three. Most of us have the ability to homeostatically control copper. However, some do not have that ability.

“It all has to do with an enzyme called metallothionein that is genetically expressed. Some people don’t have that system working,” Walsh explains. “These persons have copper overload, which we find virtually in every autistic patient, most patients with schizophrenia and almost everyone with postpartum depression.

That’s a recipe for very high norepinephrine — which means anxiety and depression — and low dopamine (a feel-good neurotransmitter), which is a hallmark of ADHD … a nasty combination.

We find the sociopaths innately have low copper levels. People who have undermethylation tend to have low normal copper levels … The good news for mental disorders is that there are more than 100 really important biochemicals in the body, but only a few dominate mental disorders.

If we had to do lab testing for 100 of them, it would be really difficult. If we had to adjust the levels of these and normalize 100 different factors, it would make life very difficult. But we found that by just focusing on maybe seven or eight nutrient factors, we could help 95 percent of the patients we see with nutrient therapy.”

How to Measure Your Zinc and Copper Status

Zinc experts typically agree that plasma zinc provides the most accurate measurement. The taste test has some minor value but is among the least reliable. To accurately measure copper, serum copper is the way to go, and most labs throughout the world provide good copper assays.

Walsh recommends doing a ceruloplasmin test at the same time, because then you can determine how much free radical copper you have, which gives you a good indication of your level of oxidative stress. A high sensitivity C-reactive protein (CRP) test would also be useful as a marker of inflammation.

“By the way, oxidative stress runs through every single mental disorder we see, without exception,” Walsh says. “Every one of them seems to have extraordinary oxidative stress — schizophrenia, bipolar disorder, a violent child or an autistic child.”

Unfortunately, our modern lifestyle strongly promotes oxidative stress, with processed foods, processed vegetable oils, excessive net carbs and excessive protein being some of the most potent factors. This kind of diet causes a reduction in ketones and a radical increase in reactive oxygen species and secondary free radicals.

Exposure to non-native electromagnetic fields, glyphosate and other pesticides, fluoride-contaminated water and other toxic exposures only add to the problem. Typically, copper and ceruloplasmin levels tend to go hand in hand, being either high or low together. The ideal level for copper, with respect to mental health, is somewhere between 75 and 100 micrograms per deciliter (mcg/dL) in serum. The ideal amount of ceruloplasmin has to do with whatever your level of copper is.

Ideally, the percentage of copper in your ceruloplasmin should be around 85 to 90 percent. “It’s really great to do both simultaneously because then you have a really good picture of not only the copper situation, but also the level of oxidative stress,” Walsh says.

Related: Homemade Calcium and Magnesium

The Importance of Methylation in Mental Health

Walsh was among the first people to alert the world to the importance of methylation in mental health, especially autism. The No. 1 causes of undermethylation are single-nucleotide polymorphisms (SNPs) or mutations in the enzymes for the one-carbon cycle (the methylation cycle).

“The No. 1 factor is the methylenetetrahydrofolate reductase (MTHFR), which is one of the enzymes. That’s the rate-limiting step for that whole cycle, for most people,” Walsh explains. “Genetic testing services such as 23andMe can provide this kind of information.

However, most human beings have enormous numbers of SNPs. They’ve already found 10 million snips (or mutations) in the human genome. Every human being has thousands of these SNPs. A really high percentage of people have even the more serious MTHFR SNPs — the C677T, the A1298C that people are always talking about.

The thing that is often mistaken by nutritional scientists is that if a person has the homozygous, the double copies of the C677T, it doesn’t necessarily mean they’re undermethylated. It certainly doesn’t mean that they will benefit if you give them methylfolate. That’s one of the problems that we’re finding.

The reason is epigenetics. You have to consider the epigenetics and the methylation at the same time. There are three nutrient factors that affect epigenetics more than anything else: folates, methionine and S-adenosylmethionine (SAMe). These have a really powerful impact on epigenetics.”

How Folates Affect Epigenetics

Folates are serotonin reuptake promoters. However, even if an individual is undermethylated and has a problem related to low serotonin activity, such as depression or anxiety, folates should not be given, Walsh warns. The reason? If you give folate, their methylation will improve and the patient will actually get worse.

Related: Mental Health, Physical Health & B Vitamins – Nature’s Valium

The reason for this worsening is because, epigenetically, folates act as deacetylase inhibitors and sharply lower serotonin activity. Most autistic individuals will not have a serotonin problem and will thrive on methyl folate. However, an estimated 10 percent of autistic children and adults do have a serotonin issue and will severely regress if given methyl folate.

“We’ve had thousands of patients who were undermethylated depressives. I’ve seen more than 3,000 cases of clinical depression. I’ve got this huge database. The largest phenotype … is undermethylation.

But if you gave them any form of folate, they would get worse. Their methylation would improve, they would get worse, because it has a dramatic impact on serotonin reuptake. In contrast, methionine and SAMe are natural serotonin reuptake inhibitors.

They do essentially the same thing that Prozac and Paxil do. Folates have the opposite effect. Folates are wonderful if you want to knock dopamine level down in schizophrenics or people who have high anxiety — overmethylated people. It’s counterintuitive because folates are excellent methylating agents..”

To reiterate, some undermethylated people are intolerant to folates, and some overmethylated people thrive on folates even though folates improve methylation. As you can see, there are epigenetic complexities involved here, making self-diagnosis and self-treatment highly inadvisable.

It could be quite risky to take these bits and pieces of information and try to apply them on your own. There are simply too many variables. So, the bottom line here is to make sure you’re being treated by a knowledgeable professional.

Heavy Metals and the Autistic Brain

Walsh has tested 6,500 autistic patients. As a group, they have much higher toxic metal levels than their siblings or the general population. Walsh believes their toxic burden is likely due to an inborn predisposition that makes them more likely to accumulate toxins and/or vulnerable to the effects of toxins.

“Thousands of these parents, maybe more than half, told a very sad story of how they had a child who was developing normally, was beginning to speak and was singing and charming their grandparents. Then maybe the child got sick.

They took him to a pediatrician and the pediatrician — I’ve heard this story hundreds of times — said, ‘Oh, you’re behind on your shots. You’re behind on your vaccinations.’ They took a sick child and gave them multiple vaccinations, at that time, with thimerosal and mercury.

Hundreds of these families said that within a day or two, their child changed forever. Lost all speech, the personality changed, they became sick. They became intolerant to served foods. They were just very troubled little human beings.

When they went to specialists, eventually they wound up with the diagnosis of autism and were told that it was incurable and that there was no hope really for recovery. We’ve seen a lot of human misery just talking with these families. It’s just a shocking and terrible thing.”

Walsh suspects autistic children have an insufficiency of natural antioxidants such as glutathione and metallothionein, rendering them more vulnerable to the effects of environmental exposures, including vaccines and poor diet. It’s worth noting that 1 in 3 children diagnosed with autism does not have true autism caused by epigenetic variations.

Many of these children have a good chance of recovery, whereas classic Kanner autism is a permanent, life-long epigenetic condition (named after Leo Kanner, who discovered autism in the 1940s1), although some measure of improvement can be made even in these cases.

Related: How To Detoxify and Heal From Vaccinations – For Adults and Children

On Thimerosal

Walsh has also investigated the thimerosal issue, looking for evidence of mercury toxicity in the brains of autistic children. In fact, he was the first person to actually measure mercury in autistic brains.

He was able to receive brain tissue samples from Johns Hopkins, and using the Argonne facility called the Advanced Photon Source, he did over 1 million chemical analyses on brain tissue from autistic and non-autistic children. Every autistic child analyzed had received thimerosal-containing vaccinations.

However, no mercury could be found in the brain tissue. One explanation for this is that the tests were done years after the vaccinations. The half-life of mercury in the human body is 42 days. The half-life of ethyl or methyl mercury in the brain is 70 days.

“I think what it amounts to is that mercury is a terrible poison. It’s a terrible insult,” he says. “I think these vulnerable kids should never be exposed to it. However, it doesn’t stay in the body and it doesn’t do continuing damage. I think after a year or so, it has left the body, even though there are tens of thousands of families who are trying therapies that will take the mercury out of their child’s brain when it’s no longer there.”

Metallothionein Promotion Nutrient Therapy for Autism

The fact that autistic children tend to have extraordinary copper and zinc imbalances means their metallothionein protein is not functioning. Metallothionein is required for homeostatic control of copper and zinc. Walsh has developed a metallothionein promotion nutrient therapy: a formulation of 22 nutrients known to enhance genetic expression and function of metallothionein. This protocol has been used on more than 2,000 autistic patients, with measurable improvements in outcome.

“The most important antioxidants in the brain are somewhat different than the rest of the body. I call them the three musketeers. It’s glutathione, metallothionein and selenium. It’s specific to the brain,” he explains.

Technically, selenium is not an antioxidant per se, but it does increase glutathione levels and enhances the function of metallothionein and, in the brain, glutathione and metallothionein work together. Glutathione is your first line of defense. The problem is, autistic children typically have a poor diet (it’s hard to get them to eat anything) and with the oxidative overload, they quickly run out of glutathione. When you run low on glutathione in your brain, your metallothionein level increases.

“Metallothionein doesn’t work unless you have oxidized glutathione. It’s a hand in glove situation. It’s the backup system for glutathione in the brain, and we know that without selenium, that whole system doesn’t work well,” Walsh explains.

I take selenium every day. It’s a trace mineral, so you don’t need much, up to about 200 mcg per day, and you definitely need to be mindful not to overdose. As noted by Walsh, of all the trace metals, selenium has the narrowest division between deficiency and overload, so you need to be careful when supplementing.

Zinc also needs to be normalized, as it is the No. 1 factor for enabling metallothionein to function and support glutathione. According to Walsh, for mental and physical health, you need a plasma zinc level between 90 and 130 mcg/dL. Many mental patients have a genetic weakness in zinc normalization; they’re born with zinc deficiency, and need far higher amounts than typical to maintain a healthy zinc level.

Related: Total Nutrition – Make your own Homemade Multivitamin and Mineral Formula

Changing the Face of Psychiatry

Walsh is convinced the use of psychiatric medication will eventually fade away as we learn more about normalizing brain function through nutritional interventions. “These powerful drugs … they do not normalize the brain. They cause an abnormal condition,” he warns. “They might correct depression or anxiety, but you wind up with something that’s not normal.”

The Walsh Research Institute is a public charity with no financial interests, and they are slowly but surely helping to change mainstream psychiatry. Walsh has given talks at the highest levels, including the Surgeon General’s office, the U.S. Senate and the National Institutes of Health (NIH). He’s also spoken at American Psychiatric Association (APA) annual meetings several times.

“The last time I went there, they finally listened to me … I was there about two and a half years ago. I gave an invited talk on depression. I basically explained to them they’re doing depression wrong. They actually listened to me. I showed them our huge chemistry database and explained that depression is a name given to at least five completely different disorders, each involving different symptoms and each involving different neurotransmitters that are malfunctioning.

Then I described each one of these biotypes and actually showed them that if they would simply do some inexpensive blood and urine testing, they could identify which people would be good candidates for selective serotonin reuptake inhibitors (SSRIs) or which ones would do better on benzodiazepine, but even more importantly, how they can correct it with nutrients.”

There were 17,000 psychiatrists at this meeting from all over the world, and Walsh was 1 of 4 speakers at a well-attended session. Afterward, there was tremendous demand for more information, which gives hope. Walsh also offers a training program for doctors. In the U.S., 45 psychiatrists went through the program last year. In all, 500 physicians and psychiatrists in 32 countries have taken his program so far.

Why SSRIs Induce Violence

One major problem with SSRI antidepressants is the risk of self-harm and aggression as a side effect. Overmethylated, low-folate depressors are intolerant so SSRIs, and evidence suggests this genetic intolerance may have been a factor in many school shootings. Walsh, who has studied this phenomenon, notes 42 of the 50 major school shootings in the U.S. since 1990 were done by teens or young adults taking an SSRI.

“I discussed this … before the APA … I tried to explain to them that they … can do a blood test; they can find out which children or which adults are more likely to become violent if they get an SSRI. I’ve written about this several times; published it in magazines …

If you buy Prozac or Paxil, the insert inside warns that some people … are prone to suicidal or homicidal behavior. We now know which ones they are!”

More Information

To learn more, visit www.WalshInstitute.org. There you can also purchase Walsh’s book, “Nutrient Power: Heal Your Biochemistry and Heal Your Brain.” Questions and information requests can be sent to Dana@WalshInstitute.org, or you can call (630) 506-5066.

“Our website has a resources section that recommends quality labs, compounding pharmacies and a list of doctors who we’ve trained, who are now able to do this kind of therapy,” Walsh says.