The effect was seen if the person was depressed before or after diagnosis of the disease.
Nearly 25,000 people with coronary artery disease were tracked over an average of 10 years and about 15 per cent of them ended up being diagnosed with depression, according to a paper published in the European Heart Journal.
Dr. Heidi May, a cardiovascular epidemiologist at Intermountain Medical Centre Heart Institute in Salt Lake City, said: No matter how long or how short it was, patients were found to have twice the risk of dying compared to those who didn’t have a follow-up diagnosis of depression.
Depression was the strongest risk factor for dying, compared to any other risk factors we evaluated. That included age, heart failure, diabetes, high blood pressure, kidney failure, or having a heart attack or stroke.
We’ve completed several depression-related studies and been looking at this connection for many years.
The data just keeps building on itself, showing that if you have heart disease and depression and it’s not appropriately treated in a timely fashion, it’s not a good thing for your long-term wellbeing.”
Of more than 2,600 patients who became clinically depressed about 27 per cent did so within a year of being diagnosed with the disease. The figure was 37 per cent after five years.
And while depression seems to make the condition worse, being diagnosed is also a reason why some patients become depressed.
The reason why the chance of dying increased was not revealed by the study, but Dr. May said it was possible patients were not following their treatment plans as closely as people in good mental health. She said,
We know people with depression tend to be less compliant with medication on average and probably in general aren’t following healthier diets or exercise regimens.
They tend to do a poorer job of doing things that are prescribed than people without depression. That certainly doesn’t mean you’re depressed so you’re going to be less compliant, but in general, they tend to follow those behaviours.”
She added that depression can also cause physiological changes to the body, which could also be a factor.
(Dr. Mercola) If you suffer from frequent heartburn, chances are you’ve been prescribed a proton pump inhibitor(PPIs) such as Prilosec, Prevacid or Nexium to inhibit acid production. This, despite the fact they were never intended to treat heartburn in the first place.
PPI drugs were originally designed to treat a very limited range of severe problems,1 including bleeding ulcers, Zollinger-Ellison syndrome (a rare condition in which tumors in the pancreas cause your stomach to produce excess acid) and severe acid reflux concomitant with esophageal damage. But that hasn’t stopped them from becoming the go-to solution for everyday indigestion.
Research clearly shows PPIs are outrageously overprescribed and misused, and do far more harm than good.2,3,4,5,6,7 There are many alternative treatment strategies that can help ease this painful problem without the serious side effects associated with PPIs, which include kidney disease, pneumonia, osteoporosis, hip fractures, dementia and an increased risk for heart disease,8heart attacks9 and premature death.10
The long-term answer to heartburn and acid indigestion is to restore your natural gastric balance and function. The most important step is to eat real food, as processed foods and sugars are a surefire way to exacerbate acid reflux. Reseeding your gut with beneficial bacteria, either from traditionally fermented foods or a high-quality probiotic supplement, is also important. Aside from that, there are a number of natural substances that can help address the root of the problem.
What Causes Heartburn?
Digestion of food begins in your mouth as the food is broken into smaller pieces and mixed with saliva before traveling down your esophagus and into your stomach. Once in your stomach, the food mixes with hydrochloric acid, which is required to break the food down into even smaller pieces from which your small intestines can extract nutrients.11
Heartburn, also referred to as acid reflux, gastroesophageal reflux disease (GERD) or peptic ulcer disease, is characterized by a burning sensation originating behind your breastbone, sometimes traveling up into your throat. In some cases, this burning pain can be severe enough to be mistaken for a heart attack.
When food passes through your esophagus into your stomach, a muscular valve called the lower esophageal sphincter (LES) closes, preventing food or acid from moving back up. The painful effect associated with heartburn occurs when the LES relaxes inappropriately, allowing acid from your stomach to reflux backward into your esophagus and burn tissue that cannot withstand the low pH of the acid.
While the conventional rationale states that this reflux is caused by excessive amounts of acid in your stomach, that’s actually an extremely rare situation, typically occurring only if you have the rare disease known as Zollinger-Ellison syndrome. Instead, the vast majority of acid reflux cases are related to one or more of the following:
•Helicobacter pylori (H. pylori) imbalance. One of the explanations for why suppressing stomach acid is so ineffective — and there are over 16,000 articles in the medical literature attesting to this — is that when you decrease the amount of acid in your stomach, you suppress your body’s ability to kill the helicobacter bacteria.
While H. pylori can be part of your normal healthy microbiome, it can cause problems, including symptoms of acid reflux, if there’s an overgrowth of it. This typically occurs as a result of a poor diet. Taking a betaine hydrochloric supplement (available in health food stores without prescription) will not only improve digestion but will also help kill the helicobacter, thereby normalizing your symptoms.
•Hiatal hernia.13 If you have a hiatal hernia, physical therapy on the area may work, and many chiropractors are skilled in this adjustment.
•Food allergies can also be a contributing factor to acid reflux, so eliminate common culprits such as caffeine, alcohol, and nicotine.
Acid reflux can also imitate symptoms of gallbladder disease.14 Your gallbladder is located beneath your liver on the right side of your abdomen. Pain stemming from your gallbladder is typically felt just under your lower ribs on the right side, and/or in the pit of your stomach. Depending on the severity of your problem, the pain can radiate into your upper back on the right side, your chest or even your shoulder.
While heartburn will typically occur right after a meal and tends to get worse if you lie down, gallbladder pain usually sets in several hours after eating and gets worse on the in-breath. For proper diagnosis, your doctor may need to do an ultrasound on your gallbladder or other tests.
Important Considerations If You’ve Had Your Gallbladder Removed
Over 700,000 people have their gallbladder removed every year in the United States. If you happen to be one of them, it is important to realize that your gallbladder stores bile, which helps you digest and emulsify the fat you eat. If you’ve had your gallbladder removed, it’s really important to take ox bile, lipase or pancreatin — digestive enzymes that digest fat — anytime you eat a meal containing fats.15,16
Your gallbladder holds and excretes bile produced in your liver, and this bile contains the necessary enzymes to digest fats. Common signs and symptoms that your body is not digesting fats well include diarrhea, loose stools, light-colored or pale stools, bloating, nausea and indigestion after a meal.
Certain fatty foods (such as steaks or salmon) tend to be more problematic than others, but for proper digestion and absorption of fat-soluble nutrients, you really need to take a lipase or ox bile supplement with each meal. To learn more, see “Five Important Tips If You’ve Had Your Gallbladder Removed.”
Simple Test to Evaluate Your Stomach Acid Level
A simple test can be used to determine if your stomach acid level is low, and this knowledge will help you develop a plan to reduce your chronic pain. This simple test is a rough indicator of how much acid your stomach produces:
1.Mix 1 teaspoon of baking soda in 8 ounces of cold water and drink it first thing in the morning, before eating or drinking anything. The combination of baking soda and hydrochloric acid in your stomach creates carbon dioxide gas, causing you to belch.17
2.Time yourself for up to five minutes for how long it takes you to form enough gas in your stomach to belch. Belching in two to three minutes is normal; earlier and repeated belching indicates an excess of acid. If you don’t belch after five minutes, you likely don’t produce enough acid.
More accurate testing involves taking a stool sample to determine whether you might have an enzyme and/or hydrochloric acid deficiency.18 It could also identify bacterial or fungal imbalances that might contribute to your condition. If you aren’t making enough stomach acid you can take a betaine HCL with pepsin supplement. Start with one or two tablets and work your way up to around five or seven with each large meal, but make sure you don’t have any burning in your stomach. If you do, you’re taking too much.
The Problem With PPIs
PPIs inhibit the proton pump that produces hydrochloric acid. However, excess stomach acid is rarely the primary trigger of heartburn and indigestion. On the contrary, heartburn is typically indicative of insufficient amounts of hydrochloric acid. If your acid levels are low, PPIs will exacerbate the problem by decreasing acid further.
And, since hydrochloric acid (and pepsin) are necessary to break down protein in your intestinal tract, reducing acid can alter your body’s ability to absorb nutrients. Without adequate protein breakdown, you also increase your risk of dysbiosis,19 an imbalance in gut microbiome between harmful and friendly bacteria.
As these undigested protein molecules ferment in your intestines, they become food for pathogens such as H. pylori, C. difficile and Candida. An overgrowth of these bacteria may also lead to leaky gut and associated health problems. A recent study20 confirmed this risk. Compared to those not taking PPIs, participants who did had a 1.7 to 3.7 times increased risk of developing C. difficile or Campylobacter infection.
Although both of these bacteria trigger abdominal pain and diarrhea, C. difficile tends to be the more serious of the two. According to the Centers for Disease Control and Prevention (CDC), an estimated 29,000 Americans die from C. difficile infection each year.21 A meta-analysis22 looking at studies published between 1990 and 2010 also found a significant link between C. difficile infection and PPI use.
PPIs Associated With Increased Risk of Dementia
Research has linked PPIs to a number of other devastating health effects as well, including dementia. Disturbingly, cognitive changes can occur even with short-term use. In one study,23 PPIs were found to cause statistically and clinically significant impairments in the participants’ executive functions, visual memory and planning function after just one week of use.
According to research24,25,26 published in JAMA Neurology, seniors over the age of 75 who use PPIs on a regular basis had a 44 percent increased risk of dementia compared with non-users. Men were at greater risk, raising their dementia risk on average by 52 percent, compared to 42 percent for women.
One characteristic of dementia is the accumulation of beta-amyloid plaques in the brain that provoke inflammation and ultimately kill brain cells. There is now strong scientific evidence that PPIs not only increase production of beta-amyloid plaques in the brain, but slow your body’s ability to eliminate them as well.27,28,29 Two other studies concluded those taking PPIs were at greater risk of developing Alzheimer’s disease.30,31
PPIs Raise Your Risk of Heart Attack and Premature Death
Research has also linked long-term PPI use to an increased risk for heart disease32 and heart attacks — even if you have no prior history of cardiovascular disease.33,34 In one study,35 patients with GERD who took PPIs had a 16 percent increased risk of heart attack, and a two-fold increased risk of cardiovascular mortality.
The reason for this effect is thought to be due to the drug reducing nitric oxide (NO) in your blood vessel walls. NO relaxes your blood vessels, so by reducing the amount of NO, PPIs may raise your risk of a heart attack. Recent research also found PPI users were nearly 20 percent more likely to die from any cause compared to nonusers over the course of six years, and the longer the use, the greater the risk.36,37,38,39 As reported by Reuters:40
“The most likely explanation for the increased mortality risk is the side effects associated with PPIs … In terms of the mechanisms that could be involved … laboratory experiments have shown that lysosomes — tiny organs within cells that act like garbage disposals to get rid of waste — don’t function well in people taking PPIs. Other research has shown that PPIs may shorten the protective chromosome ends known as telomeres, in effect speeding up cell aging.”
Other Health Hazards Associated With PPI Use
Studies have also linked PPIs to the development of chronic kidney disease,41 increased risk of bone fractures42,43 and vitamin B12 deficiency, which in turn may lead to anemia, nerve damage, psychiatric problems and dementia. Researchers at Houston Methodist Hospital think they’ve discovered one of the reasons why PPIs can have such devastating effects on your brain, kidneys and other systems.
When different cells were grown in culture and exposed to PPIs, cells that line blood vessels demonstrated significant change.44 PPIs are taken orally and affect the proton pump in more than just your stomach walls. Blood vessels also produce small amounts of acid to break down and eliminate damaged protein molecules. When acid levels drop, microscopic debris begins to build up on the arterial walls, resulting in problems where many blood vessels are found, such as your brain, heart and kidneys.
Lead author Dr. John Cooke, chair of cardiovascular disease research at Houston Methodist Research Institute, noted:45 “I’m perplexed that the pharmaceutical industry didn’t run across this first. This is something that should have been apparent a long time ago and should have been investigated.”
How to Properly Wean Yourself Off PPIs
If you’re currently taking a PPI, do NOT quit cold turkey. Doing so can result in severe rebound effects known as rebound acid hypersecretion. It’s important to spend time detoxifying and eliminating the drug from your system. To do that, you need to gradually wean yourself off the drug.
Once you’re down to the lowest dose, start substituting with an over-the-counter H2 blocker, like Cimetidine, Zantac, Ranitidine or Tagamet. Once you’ve been taking the H2 blocker for a couple of weeks, you may start weaning yourself off these drugs as well, while introducing the alternative options to reduce your heartburn outlined below.
How to Heal GERD and Avoid Heartburn
One simple strategy to address a hydrochloric acid deficiency is to swap out processed table salt for an unprocessed version like Himalayan salt. By consuming enough of the raw material, you will encourage your body to make sufficient amounts of stomach acid naturally. Research46 has also shown that sauerkraut or cabbage juice is among the strongest stimulants for your body to produce stomach acid.
It will also provide you with valuable bacteria to help balance and nourish your gut. Having a few teaspoons of fermented cabbage juice from sauerkraut before your meal will do wonders to improve your digestion. Fresh, raw cabbage juice can also be very useful to heal resistant ulcers. To restore your natural gastric balance and function, also be sure to eat lots of vegetables and other high-quality, ideally organic, unprocessed foods.
Reseeding your gut with beneficial bacteria, either from traditionally fermented foods or a high-quality probiotic supplement is also important, as this will not only help balance your bowel flora, but can also help eliminate helicobacter bacteria naturally. Probiotics and fermented foods, especially fermented vegetables, also aid in proper digestion and assimilation of your food.
Also, beware of lectin-rich foods such as grains and legumes, as lectins are potent enzyme inhibitors.47,48 By inhibiting digestive enzymes, your digestive system will not function properly and foods will not be broken down, thereby producing or exacerbating heartburn.
Among the most problematic lectin-containing foods are wheat and other seeds of the grass family, any dairy that has A1 casein protein, beans, soy and other legumes, peanuts and members of the nightshade family such as eggplants, potatoes, tomatoes, and peppers. Grains and legumes such as black beans, soybeans, lima beans, kidney beans and lentils contain the highest amounts of lectin.
It is also crucial to avoid eating processed foods as much as possible. Be sure to concentrate on eating real foods as that is one of the most powerful strategies you have to activate biological homeostasis in your gut.
Effective Alternatives to Treat Heartburn, GERD, and Indigestion
Other helpful strategies to get your heartburn under control include the following suggestions, drawn from a variety of sources.49,50,51,52,53
Raw, unfiltered apple cider vinegar
Acid reflux typically results from having too little acid in your stomach. You can easily improve the acid content of your stomach by taking 1 tablespoon of raw unfiltered apple cider vinegar in a large glass of water.
Betaine hydrochloric acid with pepsin
Another option is to take a betaine hydrochloric supplement with pepsin.54,55 Typically, you only need a betaine supplement with meals containing protein.
You’ll want to take as many as you need to get the slightest burning sensation and then decrease by one capsule. This will improve digestion and help kill the H. pylori bacteria. As a general dosing guideline, an effective adult dose is typically five to seven capsules containing 650 milligrams (mg) of betaine with pepsin.
The only time a pepsin-free betaine supplement is recommended is when you’re sensitive to pepsin. That’s rare, however, and without pepsin the betaine will not work well, because if your stomach does not produce enough hydrochloric acid, it also will not make sufficient amounts of pepsin (the enzyme that breaks down proteins).
According to Dr. Jonathan Wright, betaine is contraindicated if you’re taking any kind of anti-inflammatory medication, such as corticosteroids, aspirin, Indocin, ibuprofen or other NSAIDs.56
The reason for this is because these drugs can damage your gastrointestinal lining. Taking a hydrochloric acid supplement can aggravate the area, raising your risk of gastric bleeding or an ulcer.57 Digestive bitters may be a safer choice in this case.
Papaya fruit or papain supplement
Papaya fruit contains papain, an enzyme that helps break down both protein and carbohydrates. It even helps break down gluten, making it particularly valuable for those struggling with gluten sensitivity.58
Pineapple or bromelain supplement
Bromelain is a proteolytic enzyme found in pineapple, and like papain, it also helps digest proteins. It also has anti-inflammatory activity and helps maintain more regular bowel movements.59
Baking soda
One-half to 1 full teaspoon of baking soda (sodium bicarbonate) in an 8-ounce glass of water may ease the burn of acid reflux as it helps neutralize stomach acid. I would not recommend this is a regular solution, but it can sure help in an emergency when you are in excruciating pain.
Aloe juice
The juice of the aloe plant naturally helps reduce inflammation, which may ease symptoms of acid reflux. Drink about one-half cup of aloe vera juice before meals. If you want to avoid its laxative effect, look for a brand that has removed the laxative component.
Ginger root
Ginger has been found to have a gastroprotective effect by suppressing Helicobacter pylori.60 It also tightens your LES, thereby preventing the reflux of stomach acid61 and reduces inflammation.62 According to a 2007 study,63 it’s also far superior to lansoprazole for preventing the formation of ulcers, exhibiting up to eight-fold greater potency over the drug.
Add two or three slices of fresh ginger root to 2 cups of hot water. Let steep for about a half-hour. Drink about 20 minutes or so before your meal.
Vitamin D
Vitamin D is important for addressing any infectious component. Once your vitamin D levels are optimized, you’re also going to optimize your production of about 200 antimicrobial peptides that will help your body eradicate any infection that shouldn’t be there.
Astaxanthin
This exceptionally potent antioxidant was found to reduce symptoms of acid reflux in patients when compared to a placebo, particularly in those with pronounced helicobacter pylori infection.64 Best results were obtained at a daily dose of 40 mg.
Slippery elm
Slippery elm coats and soothes your mouth, throat, stomach, and intestines, and contains antioxidants that can help address inflammatory bowel conditions. It also stimulates nerve endings in your gastrointestinal tract. This helps increase mucus secretion, which protects your gastrointestinal tract against ulcers and excess acidity. The University of Maryland Medical Center65 makes the following adult dosing recommendations:
•Tea: Pour 2 cups boiling water over 4 grams (roughly 2 tablespoons) of powdered bark, then steep for three to five minutes. Drink three times per day
•Tincture: 5 milliliters (mL) three times per day
•Capsules: 400 to 500 mg three to four times daily for four to eight weeks. Take with a full glass of water
•Lozenges: Follow dosing instructions on label
Deglycyrrhizinated licorice root
Deglycyrrhizinated licorice (DGL) may also be helpful, as it helps block inflammatory prostaglandins.66 As noted by Livestrong,67 “Licorice (Glycyrrhiza glabra) has been … used to treat a variety of maladies … Its ancient reputation as a folk remedy for gastric problems does have a scientific basis. This is especially true for functional dyspepsia, a condition that frequently overlaps with acid reflux.
Like acid reflux, it presents symptoms of pain in the upper abdomen, discomfort, burning and belching. Iberogast, or STW 5, and GutGard, two products whose primary ingredient is an extract of DGL licorice, have been shown to relieve symptoms of both dyspepsia and acid reflux; however, these products have many other ingredients …
Licorice must be approached cautiously because it contains the active metabolite glycyrrhiza. In large quantities, glycyrrhiza can cause a syndrome called hyperaldosteronism, which affects the adrenal glands and can cause numbness, high blood pressure and muscle weakness.”
DGL supplements contain licorice from which a substantial amount of the glycyrrhiza has been removed, making it safer for use.68 Dr. Andrew Weil recommends chewing two DGL tablets or taking half a teaspoon of DGL powder before or between meals and at bedtime. Once your symptoms are under control, taper down your dose.69
Licorice is contraindicated if you’re on diuretics or stimulant laxatives. Also, beware that licorice may reduce your potassium level, and has estrogenic activity, so women on hormone therapy or who have estrogen-dependent cancers or other reproductive conditions such as endometriosis should avoid it.70
Glutamine
Research71 published in 2009 found that gastrointestinal damage caused by H. pylori can be addressed with the amino acid glutamine, found in many foods, including beef, chicken, fish, eggs, dairy products and some fruits and vegetables. L-glutamine, the biologically active isomer of glutamine, is also widely available as a supplement.
Folate or folic acid (vitamin B9) and other B vitamins
Research72 suggests B vitamins can reduce your risk for acid reflux. Higher folic acid intake was found to reduce acid reflux by approximately 40 percent. Low vitamin B2 and B6 levels were also linked to an increased risk for acid reflux. The best way to raise your folate levels is by eating folate-rich whole foods, such as liver, asparagus, spinach, okra and beans.
A dietary supplement containing melatonin, l-tryptophan, vitamin B-6, folic acid, vitamin B-12, methionine and betaine was found to be superior to the drug omeprazole in the treatment of GERD.73 Part of the success is thought to be due to melatonin’s inhibitory activity on NO biosynthesis, which plays an important role in transient LES relaxation, which, as I mentioned earlier, is part of the real underlying problem of heartburn.
Impressively, 100 percent of patients receiving this supplement reported a complete regression of symptoms after 40 days of treatment, compared to just under 66 percent of those taking omeprazole. The authors concluded that “this formulation promotes regression of GERD symptoms with no significant side effects.”
(Natural Blaze) Eating tilapia can be toxic to your health and can cause all sorts of health problems.
Here are at least 5 reasons why you should probably avoid consuming the 4th most consumed fish in America according to the National Institute of Fisheries.
1.) Eating tilapia is worse than eating bacon (HIGH INFLAMMATORY LEVELS) according to nutritionists
You may be surprised, but some nutritionists believe that an average serving of tilapia has more fatty acid than bacon
The quantity of omega-6s in tilapia is higher than in a hamburger or bacon.
In 2008, researchers at the Wake Forest University School of Medicine released a study comparing fatty acid levels among popular farm fish. The researchers found that tilapia contained far less omega-3 fatty acid than other fish, such as salmon and mackerel.
The report stated that the “inflammatory potential of hamburger (80 percent lean) and pork bacon is lower than the average serving of farmed tilapia (100 g).” In theory, scientists believe this may contribute to heart disease, cancer, and other chronic health problems.
A 2009 study conducted by the Economic Research Service of the U.S. Department of Agriculture stated Chinese farm-raised fish are fed poultry and livestock feces.
“It is common practice to let livestock and poultry roam freely in fields and to spread livestock and poultry waste on fields or use it as fish feed,” the report said.
Researchers noted that “many of China’s farms and food processors are situated in heavily industrialized regions where water, air, and soil are contaminated by industrial effluents and vehicle exhaust.”
So how much tilapia in the U.S. actually comes from China?
You would be shocked to know the answer. According to Monterey Bay Aquarium Seafood Watch, over 95 percent of tilapia consumed in the U.S. came from overseas with a whopping 70% from China.
3) Tilapia Could Cause Alzheimer’s and Cancer
Tilapia can carry up to 10 times the amount of carcinogens as other farm raised fish. This is because of the “food” the farmers typically feed the fish is — feces, pesticides, and industrial-grade chemicals.
Additionally, the fish may contain high levels of arachidonic acid, which, in excess, has been linked to conditions like Alzheimer’s.
4) Antibiotics are used to modify the fish to grow faster
Tilapia are fed antibiotics, malachite green and methyl testosterone hormones to keep the population safe and to grow them faster. The chemical dye malachite green is banned for food use since 1983 because it is a suspected carcinogen.
In 2007, the FDA halted imports of farmed fish from China after finding antimicrobials — nitrofuran, malachite green, gentian violet, and fluoroquinolone.
Nitrofuran, malachite green and gentian violet are chemicals that are known to treat fungal infection and have been shown to be carcinogenic with long-term exposure, while fluoroquinolones are used to increase antibiotic resistance.
Researchers have found that dioxin, which is linked to the development and progression of cancer is found within Tilapia due to the food farmers feed it. However, that doesn’t mean that Tilapia as a whole all contains contaminants it all depends on where it was raised and harvested over all.
So what are your alternatives to tilapia?
It is always best to eat wild-caught fish. If you choose to buy farmed fish, then you should look for fish that are free of hormones, antibiotics, pesticides, and are certified by the Marine Stewardship Council.
Even so, the best solution is to avoid tilapia altogether. I wouldn’t want to eat feces or antibiotics, would you?
(Mercola) Allergies are your body’s reaction to a protein (allergen) and are a sign your immune system is working overtime. According to the Allergy and Asthma Foundation of America,1 nasal allergies affect nearly 50 million people in the U.S., and that number is growing. As many as 30 percent of adults and 40 percent of children suffer from allergic diseases, including asthma.
These conditions are the fifth leading chronic disease in the U.S. and the third chronic disease in children under 18. In 2010, Americans with allergic rhinitis spent nearly $17.5 billion on health care related to the condition, lost more than 6 million work and school days and had nearly 16 million doctor visits.2
During the second encounter with an allergen, your body is ready to react, sending a powerful cocktail of histamine, leukotrienes and prostaglandins to protect your body. They trigger a cascade of symptoms associated with allergies, such as sneezing, sore throat, runny nose and itchy, watery eyes. Histamine may also cause your airways to constrict, triggering an asthma response or hives.
Pollen is one common allergen that triggers this reaction, but other protein molecules may as well, including mold spores, dust mites, pet dander, cockroaches, and cleaning and personal care products. The activation of this allergic response may be related to your dietary intake and your gut microbiome. Recent research has identified a higher risk of allergies and asthma in children born to mothers who ate high amounts of sugar during their pregnancy.3
Sugar During Pregnancy Increases Your Child’s Risk of Allergies
Researchers at Queen Mary University of London evaluated survey data from nearly 9,000 mother-child pairs in the ongoing Avon Longitudinal Study of Parents and Children, tracking the health of families with children born between April 1, 1991, and December 31, 1992.4 Lead author Annabelle Bedard, Ph.D., commented on what triggered the researchers to evaluate the association between sugar and allergies:5
“The dramatic ‘epidemic’ of asthma and allergies in the West in the last 50 years is still largely unexplained — one potential culprit is a change in diet. Intake of free sugar and high fructose corn syrup has increased substantially over this period. We know that the prenatal period may be crucial for determining risk of asthma and allergies in childhood and recent trials have confirmed that maternal diet in pregnancy is important.”
Using self-reported estimates of sugar intake from questionnaires, the researchers calculated the amount of sugar the mothers ate during their pregnancy and compared this against the number of children diagnosed with allergies or asthma by age 7. Sixty-two percent of the children did not have allergic reactions, 22 percent had common allergies and 12 percent had asthma.
As a comparison, 10 percent of children in the U.S. were diagnosed with asthma in 2010, six years prior to this analysis.6 When the children were grouped into those with the lowest sugar intake during pregnancy (less than 34 grams or 7 teaspoons) and those with the greatest (over 82 grams or 16 teaspoons) the researchers discovered that children whose mothers ate the highest amounts had a 38 percent increased risk of allergies and a 73 percent higher risk of becoming allergic to two or more allergens.7
Women who ate high amounts of sugar were also twice as likely to have children who developed allergic asthma.8 Co-author Seif Shaheen, Ph.D., said:9
“We cannot say on the basis of these observations that high intake of sugar by mothers in pregnancy is definitely causing allergy and allergic asthma in their offspring. However, given the extremely high consumption of sugar in the West, we will certainly be investigating this hypothesis further with some urgency.”
Impact of Asthma on Your Community
Asthma is a chronic lung disease that inflames the lining of your lung tissue and narrows the airways. The inflammation in your lung tissue is sensitive to environmental stimuli, also called triggers, which differ from person to person.10 Allergy triggers include dust mites, cockroaches, mold, pet dander and pollen.11
However, you may develop an asthma exacerbation from triggers other than allergic proteins. For instance, strong irritants, such as chemical sprays, perfumes and tobacco smoke or scented products may irritate your lung tissue and narrow your airways. Other triggers include cold weather, exercise, upper respiratory infections, food sensitivities and stress.
In the featured study, researchers found children whose mothers ate high amounts of sugar while pregnant developed asthma triggered by allergens and not by fragrances, cold weather, exercise, infections or food sensitivities. In the past 30 years, the incidence of asthma has increased worldwide. While the condition is generally accepted as costly, some countries do not consider it a health care priority.12
The total cost of treatment and lost work and school to society is difficult to estimate, due in part to different definitions and characterizations of the conditions and different assessments of the socioeconomic impact on society. Although variable from country to country, an average cost per patient in Europe is $1,900, while in the U.S. the cost hovers near $3,100.13
Vitamin D During Pregnancy Helps Reduce Asthma Risk
Low vitamin D levels in children who have asthma may increase the number of severe exacerbations they suffer, including the need for a trip to the hospital.14 A previous study, which followed over 1,000 children for nearly four years, found vitamin D insufficiency was linked to a 50 percent increased risk of a severe asthmatic attack necessitating a visit to the emergency room or hospitalization.
A more recent study15 published in the Journal of Allergy and Clinical Immunology also links low vitamin D levels in pregnant women to a higher risk of asthma in their children.16 This study supports similar findings from Harvard Medical School,17 in which vitamin D intake in over 1,100 mothers from the Northeastern U.S. was assessed. Children from mothers whose intake was higher during pregnancy had a decreased risk of recurrent wheezing by age 3, whether the vitamin D was from diet or a supplement.
The Journal of Allergy and Clinical Immunology study evaluated the effect of using an oral supplement of vitamin D-3 during the second and third trimester of pregnancy at nearly 4,000 IUs higher than the recommended daily intake of 400 IUs.18 After birth, researchers took a sample of the cord blood, testing the newborn’s innate immune system response known to provide the baby with long-term protection against environmental pathogens.
The samples from babies whose mothers had taken the higher supplemental dose of 4,400 IUs of vitamin D-3 responded with a healthier innate cytokine response and greater IL-17A production after T lymphocyte stimulation. The researchers believe this would likely lead to improved respiratory health as the child grows, since past research has linked a strong immune response with a reduction in asthma.
The lead researcher, Catherine Hawrylowicz, Ph.D., professor of immune regulation in allergic disease at King’s College London, commented on the importance of the results as it relates to both the health of future children and the importance of investigating further links between vitamin D and immunity:19
“The majority of all asthma cases are diagnosed in early childhood implying that the origin of the disease stems in fetal and early life. Studies to date that have investigated links between vitamin D and immunity in the baby have been observational.
For the first time, we have shown that higher vitamin D levels in pregnancy can effectively alter the immune response of the newborn baby, which could help to protect the child from developing asthma. Future studies should look at the long-term impact on the immunity of the infant.”
Impact of Sugar on Your Body
Sugar is 50 times more potent than total calories in explaining the rising rates of diabetes worldwide, explains Dr. Robert Lustig in this short video. While both glucose and fructose are sweet, they are two different molecules.
Research demonstrates not only the detrimental effect sugar has on your developing baby and their future health, but also on your own health. Despite the American Heart Association’s seal of approval on products that meet or exceed their own recommended daily limit on sugar, there is no nutritional reason to eat foods with added sugar.
In fact, the opposite is true. Diets high in net carbohydrates and added sweeteners may do far more than spike your blood glucose and insulin levels. Sugar will overload and damage your liver. High levels of sugar in your body will also trigger metabolic syndrome, a combination of weight gain, abdominal obesity, rising cholesterol levels and elevated triglycerides.
Eating a diet rich in net carbohydrates and excess sugars has also been linked to hypertension. As your insulin and leptin levels rise in response to sugars, your blood pressure also rises. Your body uses magnesium to fully relax your blood vessels, but your body is unable to store magnesium as you become resistant to insulin from a diet rich in sugar. When your body doesn’t have enough magnesium to relax your blood vessels, your blood pressure also rises.
Eating high amounts of sugar is also linked to brain-related health issues, such as depression, learning disorders, memory problems and food addiction. Sugars trigger the reward center in your brain, leading to cravings that may rival cocaine addiction in some individuals.20 However, not all sugars have identical effects. For instance, fructose may activate your brain to increase your interest in food, while glucose triggers your brain’s satiation signal.
Your Gut Microbiome and Allergies
High sugar intake also affects the growth of bacteria in your gut. In an evaluation of data from market research firm Euromonitor, researchers found people in the U.S. ate more sugar per person than any other country evaluated.21 The average person in the U.S. consumes more than 126 grams of sugar each day, nearly twice the amount consumed by 54 monitored countries and twice the amount recommended by the World Health Organization.
Researchers have demonstrated that diets rich in sugar will alter your gut microbiome,22,23 likely since your beneficial bacteria thrive on fiber and pathogenic bacteria thrive on sugar. Increasing the amount of sugar to the diet of mice transplanted with human fecal material demonstrated the gut microbiome would change dramatically within 24 hours of adding sugar to their diet.24
Scientists have found infants who go on to develop allergies start with early-life abnormalities in their gut microbiome and microbial function.25 While research continues to find links between healthy gut microbiota and a reduction in allergic response in adults and children, the evidence to date suggests that your gut microbiome is a significant target in the prevention and management of allergic asthma.26
In a recent scientific review, scientists found an association between immune-regulated epigenetic imprinting from mother to child during pregnancy that may support the immune system of the growing child after birth.27
However, if your gut microbiome is altered from high intake of sugar and net carbohydrates, this may alter your body’s ability to support the growing immune system of your child. In yet another study, doctors were able to associate altered intestinal microbiota with the development of asthma and allergies in children, suggesting the mother’s immune system may also play a role.28
Break Free From Sugar
Research supports making a break from processed foods and added sugars in your diet to optimize your health and the health of your children. While sugar is an additive that can be challenging to reduce or eliminate from your diet, the benefits to your overall health, energy level and brain function may become rapidly evident, helping to motivate your efforts.
If you currently eat a lot of sugar, there’s a good chance you’re struggling with sugar addiction. If so, I highly recommend trying an energy psychology technique called Turbo Tapping. It has helped many “soda addicts” kick their sweet habit, and it should work for any type of sweet craving you may have.
As you begin eliminating sugar from your diet, be sure to avoid most processed foods, as added sugar can be found in nearly 74 percent of processed foods under more than 60 different names.29 If you’re already fighting diabetes, heart disease, high blood pressure or are overweight, you would be wise to limit your total fructose and sugar intake to 15 grams per day until your condition has normalized.
For all others, I recommend limiting your total fructose to 25 grams or less per day. As you move toward limiting your sugar intake, here are several tips to help reduce cravings and help you on your journey to good health:
Exercise: Anyone who exercises intensely on a regular basis will know a significant amount of cardiovascular exercise is one of the best “cures” for food cravings. It always amazes me how my appetite, especially for sweets, dramatically decreases after a good workout. I believe the mechanism is related to the dramatic reduction in insulin levels that occurs after exercise.
Organic, black coffee: Coffee is a potent opioid receptor antagonist, and contains compounds such as cafestol — found plentifully in both caffeinated and decaffeinated coffee — which can bind to your opioid receptors, occupy them and essentially block your addiction to other opioid-releasing food.30,31 This may profoundly reduce the addictive power of other substances, such as sugar.
Sour taste: Simply tasting something sour, such as cultured vegetables, helps reduce sweet cravings, too. This is doubly beneficial, as fermented vegetables also promote gut health. You can also try adding lemon or lime juice to your water.
(Natural News) More than 25 million American adults – roughly 11.2 percent of the population – report having chronic pain, according to the National Institutes of Health. This epidemic has triggered an unprecedented national spike in the use (and abuse) of painkillers – including over-the-counter drugs and prescription opioid medications.
Tragically, 44 people die in the United States every day as a result of prescription opioid overdose – while non-narcotic medications such as acetaminophen and ibuprofen carry risks of their own, including damage to the stomach and liver. But, according to Charles Gant, MD, PhD, the solution to the problem of chronic pain and painkiller use could lie within our own bodies.
On the next NaturalHealth365 Talk Hour, Dr. Gant will expose the entire truth about painkillers and outline a better way to eliminate chronic pain.
Neurotransmitters hold the key to relief from chronic pain and addiction
According to Dr. Gant, drugs simply mimic the actions and effects of neurotransmitters, or chemical messengers in the brain. But depletion and deficiency of these neurotransmitters can cause increased awareness of pain, and trigger cravings and addictive behavior. The key to relief, says Dr. Gant, is restoring proper biochemical balance in the brain – which can break the cycle of addiction.
For instance, proper levels of serotonin in the brain can ensure stable mood and restful sleep. The neurotransmitter GABA also has a calming effect – which is mimicked by Valium and other benzodiazepines.
Endorphins and enkephalins, which are mimicked by opiate drugs such as oxycodone, help with relief of pain and create a sense of well-being.
According to Dr. Gant, there is even a “natural nicotine” – acetylcholine – in the body, as well as a form of “natural marijuana,” the endocannabinoid system.
When we take the actual drugs that mimic the neurotransmitters, says Dr. Gant, the brain no longer feels impelled to create them. As a result, it produces less and less of them. “Physical substances cause physical changes in the brain,” Dr. Gant reports.
On the next NaturalHealth365 Talk Hour, Dr. Gant reveals WHY painkillers can be ineffective (and dangerous) plus a more natural way to feel better.
Better nutrition is the key to ending addiction for life
Dr. Gant, who has helped over 7,500 patients, says that his comprehensive approach – which combines neuro-nutritional protocols, detoxification and genetic interventions – has led to a clinical outcome rate of 83 percent – as opposed to the traditional rate of 10 to 30 percent achieved by many detoxification and rehabilitation facilities.
Proper supplementation of nutrients such as herbs, vitamins and amino acids can help replenish neurotransmitters, thereby normalizing and restoring deficiencies that spur cravings.
For example, phenylalanine helps to restore enkephalins and endorphins, deficiencies of which can trigger the abuse of opiate painkillers – as well as of sweets, starches and nicotine. Both phenylalanine and the amino acid tyrosine also help to restore dopamine and norepinephrine – shortages of which can lead to cravings for stimulants such as caffeine, cocaine and amphetamines.
In addition to rebuilding neurotransmitters, Dr. Gant has developed a detoxification program built on proper nutrition. It’s a safe (and effective) way to restore your health. Join us for a great show.
This week’s guest: Charles Gant, MD, PhD, integrative doctor and expert on nutrition, addiction and chronic pain
Discover the truth about painkillers and how to end addiction naturally – Sun. Jul. 23
Charles Gant, MD, PhD is an integrative physician, author and educator. Practicing contemporary/alternative and functional medicine for over 30 years, Dr. Gant focuses on finding the root cause of disorders, while assisting patients in maximizing their genetic potential. He received his M.D. from the University of Virginia Medical School, and received postgraduate training in family practice, psychiatry and psychology.
Currently the chief science officer of the Academy of Functional Medicine, Dr. Gant is a leader in Precision Medicine, a cutting-edge medical system of prevention and treatment that takes into account individual differences in genomics, environmental stressors and lifestyles. Dr. Gant is also the author of several books including, “End Your Addiction Now: The Proven Nutritional Supplement Program that Can Set You Free.”
