The US Opioid Epidemic — A War of a Different Kind

(Dr. Mercola) The opioid epidemic — which between 2002 and 2015 alone claimed an estimated 202,600 Americans’ lives1 — shows absolutely no signs of leveling off or declining. On the contrary, recent statistics suggest the death toll is still trending upward, with more and more people abusing these powerful narcotics. The most common drugs involved in prescription opioid overdose deaths include2 methadone, oxycodone (such as OxyContin®) and hydrocodone (such as Vicodin®).

This dangerous class of drugs promises relief from pain and is filling a hole in human hearts and souls everywhere. According to the most recent data3 from the U.S. Centers for Disease Control and Prevention (CDC), overdose cases admitted into emergency rooms increased by more than 30 percent across the U.S. between July 2016 and September 2017. Overdose cases rose by:4

  • 30 percent among men
  • 31 percent among 24- to 35-year-olds
  • 36 percent among 35- to 54-year-olds
  • 32 percent among those 55 and older
Related: Trump Wants Death Penalty For Dangerous Drug Dealers – But who Are the Dangerous Ones?

In the Midwest region — Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota and Wisconsin — overdose cases rose by 70 percent and opioid-related mortality by 14 percent. Large cities also saw a 54 percent increase in overdose cases in that same timeframe. According to CDC officials, the results are “a wake-up call to the fast-moving opioid overdose epidemic.’’

‘The Opioid Diaries’

Curiously, opioid abuse appears to be a uniquely American problem. As noted in a recent write-up in New York Magazine,5 the U.S. “pioneered modern life. Now epic numbers of Americans are killing themselves with opioids to escape it.” I’ve written about opioid misuse and addiction on many occasions in recent years, and it seems one cannot discuss this issue enough. Many are still unaware of the dangers involved with filling that first prescription.

As an indication of the need for awareness, the March 5 issue of Time magazine, “The Opioid Diaries,”6 is aimed at exposing the national crisis. For the first time in the magazine’s history, an entire issue is devoted to a single photo essay — the work of photojournalist James Nachtwey, who has documented stories for Time for over three decades. In “The Opioid Diaries,” Nachtwey’s photos detail the stark reality of this all-American crisis.

He and editor Paul Moakley spent months traversing the U.S., interviewing over 200 people along the way. As noted by a deputy sheriff who has seen more than his fair share of the fallout of this epidemic, opioid addiction doesn’t discriminate. “It’s not just the guy who’s never worked a day in his life,” he says. “It’s airline pilots. It’s teachers. I’m sure there’s law enforcement, firemen out there hooked on it. It’s Joe Citizen that’s dying.”

Related: Opioids No Better than NSAIDs for Chronic Back or Arthritis Pain

A Country in Crisis

Here are some statistics about the U.S. opioid epidemic that really ought to get everyone’s attention:

Leading cause of death for younger Americans

Drug overdoses are now the leading cause of death among Americans under the age of 50.7

Annual death toll greater than entire Vietnam War

Preliminary data for 2016 reveals the death toll from drug overdoses may be as high as 65,000,8 a 19 percent increase from 2015; the largest annual increase of drug overdose deaths in U.S. history, and a number that exceeds both the AIDS epidemic at its peak and the death toll of the Vietnam War in its entirety.9

That much-opposed war claimed the lives of 58,000 American troops. Now, we’re suffering a death toll exceeding that of the Vietnam War each and every year, courtesy of a drug addiction epidemic created by the pharmaceutical industry.

Deadlier than breast cancer

Opioids, specifically, killed 33,000 in 2015,10,11,12 and 42,249 in 2016, which is over 1,000 more deaths than were caused by breast cancer that same year.13

Synthetic opioid abuse skyrocketing

Deadly overdoses involving fentanyl, an incredibly potent synthetic opioid, rose by 50 percent between 2013 and 2014 and another 72 percent between 2014 and 2015. Over 20,000 of the drug overdose deaths in 2016 were attributed to fentanyl and other synthetic opioids.14 In Rhode Island, New Hampshire and Massachusetts, fentanyl was responsible for at least 70 percent of all opioid-related deaths between July and December 2016.15

While some users will buy fentanyl on purpose, others buy tainted wares and end up taking it without knowing the risks. This is a critical problem, as fentanyl is so potent just a few grains can be deadly.

An inexpensive fentanyl test strip can check for the presence of the drug, and trials where test strips have been given to users show they’re more likely to cut back on the amount they’re taking when they know it’s tainted with fentanyl. As such, fentanyl testing can be employed as “a point-of-care test within harm-reduction programs” aimed at lowering the death toll.16

Significant factor in unemployment rates

Opioid abuse has been identified as a significant factor in rising unemployment among men, accounting for 20 percent of the increase in male unemployment between 1999 and 2015.17 Nearly half of all unemployed men between the ages of 25 and 54 are using opioids on a daily basis.18

Americans use vast majority of global opioid supplies

Americans consume 99 percent of the hydrocodone sold worldwide, and 81 percent of all oxycodone — approximately 30 times more than medically necessary for the population size of the U.S.19 A number of different statistics convey this massive overuse.

For example, in a five-year span, between 2007 and 2012, 780 million hydrocodone and oxycodone pills were shipped to West Virginia, which has just 1.8 million residents.20 More than 1 in 5 Americans insured by BlueCross BlueShield were prescribed an opioid in 2015, and insurance claims involving opioid dependence rose by nearly 500 percent between 2010 and 2016.21

Declining life expectancy

Life expectancy for both men and women in the U.S. has declined two years in a row,22,23 and this decline is largely attributable to the opioid crisis. Just as the opioid epidemic, declining life expectancy is a uniquely American phenomenon. No other developed countries has experienced this decline in life expectancy.

A Story of Misery

There are compelling reasons to suspect the opioid epidemic was purposely engineered by the drug companies that make them, and that these same companies have, and continue to, shy away from doing what’s necessary to curb the use of opioid pain killers for financially-driven reasons.

Related: NSAIDs Study Shows Side Effects are Worse Than Original Ailments

Moreover, while this was not likely planned, the industry’s misleading promotion of narcotic pain relievers appears to have coincided with a growing trend of emotional pain and spiritual disconnect, and opioids satisfy people’s need not only for physical pain relief but also psychological and existential pain relief. As noted by New York Magazine:24

The scale and darkness of this phenomenon is a sign of a civilization in a more acute crisis than we knew, a nation overwhelmed by a warp-speed, postindustrial world, a culture yearning to give up, indifferent to life and death, enraptured by withdrawal and nothingness …

[U]nless you understand what users get out of an illicit substance, it’s impossible to understand its appeal, or why an epidemic takes off, or what purpose it is serving in so many people’s lives. And it is significant, it seems to me, that the drugs now conquering America are downers: They are not the means to engage in life more vividly but to seek a respite from its ordeals … And some part of being free from all pain makes you indifferent to death itself.”

The article cites a number of firsthand accounts of the experience opioids provides — the blissful serenity of being able to stand apart from one’s psychological pain in addition to physical pain; the sensation of being connected to some deeper wellspring of peace. These are experiences typically derived from spiritual practices, and hint at a widespread lack of connectedness to the divine in general.

An Epic Failure of Government

While the drug industry deserves a large portion of the blame for creating the opioid epidemic, the U.S. government also mismanaged the situation right from the start by supporting drug companies’ efforts to make narcotic pain killers more readily available for people with nonlethal pain conditions, and its slow reaction to the problem has only allowed matters to worsen. In a recent Washington Post article, columnist David Von Drehle writes:25

“With the possible exception of alcohol, no substance on Earth has a longer track record of disastrous addiction than opium and its derivatives … Yet despite centuries of hard-won knowledge, pharmaceutical companies and prescribing physicians were allowed to make such opioids as Percocet and OxyContin widely available as treatments not just for acute pain, but for chronic discomfort.

Their fantasy of benign long-term opioid use is the root of the epidemic. Nearly 80 percent of heroin users report that prescription pain relievers were their gateway drugs … Such a failure of epic proportions by a generation of public-health officials merits a major congressional investigation to reduce the chance that anything like it ever happens again.”

Related: U.S. Life Expectancy To Decline, CDC Blames Pharmaceutical Companies

The U.S. government is further exacerbating drug use by tightening restrictions on less harmful and far safer non-narcotic alternatives such as medical marijuana, CBD oil and kratom. As noted by New York Magazine, “The iron law of prohibition, as first stipulated by activist Richard Cowan in 1986, is that the more intense the crackdown, ‘the more potent the drugs will become.’ In other words, the harder the enforcement, the harder the drugs.”

History Tells Us Prohibition Doesn’t Work

During the prohibition of alcohol, people didn’t turn to beer making. They started making hard liquor — moonshine. The same thing is happening now, as heroin — the street version of opioids — is being replaced with fentanyl, a synthetic opioid that is up to 100 times stronger than heroin. Users buy what they can get, and so the spiral of drug abuse and death continues spinning out of control.

“The critical Office of National Drug Control Policy has spent a year without a permanent director,” New York Magazine writes. “Its budget is slated to be slashed by 95 percent, and … Kellyanne Conway — Trump’s ‘opioid czar’ — has no expertise in government, let alone in drug control.

Although Trump plans to increase spending on treating addiction, the overall emphasis is on an even more intense form of prohibition, plus an advertising campaign. Attorney General Jeff Sessions even recently opined that he believes marijuana is really the key gateway to heroin — a view so detached from reality it beggars belief …

One of the few proven ways to reduce overdose deaths is to establish supervised injection sites that eventually wean users off the hard stuff while steering them into counseling, safe housing, and job training …

[W]e would have to contemplate actually providing heroin to addicts in some cases, and we’d have to shift much of the current spending on prohibition, criminalization, and incarceration into a huge program of opioid rehabilitation … We would, in short, have to end the war on drugs.”

Making Drug Use Safer Doesn’t Work Either

On the other hand, the safer you make drug use, the more drugs will be misused. That’s exactly what a recent study looking the variations in timing of expanded access to naloxone found. Naloxone is a drug that can reverse an overdose if administered quickly enough.

In 2013, states began expanding access to the drug beyond trained medical professionals, and more than 40 states now have expanded access, making it available to police officers, nonmedical emergency responders, teachers and even family and friends of the addicts themselves.

Related: NSAIDs Study Shows Side Effects are Worse Than Original Ailments

While the idea behind expanded access was to prevent deaths, by lowering the risk opioid-related overdoses shot up even more. As mentioned earlier, overdoses increased by more than 30 percent in the 14 months leading up to September 2017.

Worse, mortality increased by 14 percent in the Midwest after naloxone access was expanded, in large part due to increased use of fentanyl, which typically requires multiple doses of naloxone. Even with multiple doses, it doesn’t always work. Expanded access to naloxone has also led to more opioid-related crime, including the illegal possession and sale of opioids.

Common Pain Meds Are Just as Effective as Opioids, Study Finds

Evidence suggests opioid makers such as Purdue Pharma, owned by the Sackler family, knew exactly what they were doing when they claimed opioids — which are chemically very similar to heroin — have an exceptionally low addiction rate when taken by people with pain.

In fact, the massive increase in opioid sales has been traced back to an orchestrated marketing plan aimed at misinforming doctors about the drug’s addictive potential. The drug’s general effectiveness against pain has also been vastly exaggerated by drug manufacturers. In April 2016, the U.S. Centers for Disease Control and Prevention published a paper in which it noted that:26

“Most placebo-controlled, randomized trials of opioids have lasted six weeks or less, and we are aware of no study that has compared opioid therapy with other treatments in terms of long-term (more than 1 year) outcomes related to pain, function, or quality of life.

The few randomized trials to evaluate opioid efficacy for longer than six weeks had consistently poor results. In fact, several studies have showed that use of opioids for chronic pain may actually worsen pain and functioning, possibly by potentiating pain perception …”

More recently, government-funded research27,28,29 published in the journal JAMA earlier this month confirmed that patients taking opioids did not experience better pain-related function than those taking far safer, non-narcotic pain relievers. The study is the first to compare opioids against non-opioid pain medication for people with chronic back pain or osteoarthritic pain in the hip or knee.

Contrary to popular belief, patients who took Tylenol, ibuprofen or lidocaine actually reported less pain intensity than those taking an opioid drug such as morphine, Vicodin or oxycodone. Not surprisingly, however, opioid users were far more likely to experience adverse side effects. According to the authors:

“Treatment with opioids was not superior to treatment with non-opioid medications for improving pain-related function over 12 months. Results do not support initiation of opioid therapy for moderate to severe chronic back pain or hip or knee osteoarthritis pain … Overall, opioids did not demonstrate any advantage over non-opioid medications that could potentially outweigh their greater risk of harms.”

Treating Your Pain Without Drugs

It seems we’re not going to get anywhere with this epidemic until or unless we begin to address deeper societal issues. Most areas have lost a sense of community, and social media has only deepened the gulf between us. In many ways, the opioid epidemic appears to mirror a deeper, psychological and spiritual disconnect.

Related: Why Chronic Pain is Such a Pain and What You Can Do about It

It’s important to recognize and address our human need for life purpose, a sense of community and shared values. There are no quick fixes to existential despair. It will require a shift in mindset across society as a whole. With an eye on the big picture, it appears we really need to find ways to reinfuse meaning into our lives.

With regard to physical pain, we clearly need to have compassion. But the most compassionate treatment isn’t necessarily a narcotic pain reliever. A number of studies have already confirmed that opioids do not work well at all for chronic pain. Most recently, they were found to be no more effective than Tylenol and ibuprofen over the long term. Opioids really must be a drug of last resort, and should almost never be considered for chronic long-term use. It’s important for both doctors and patients to recognize this.

That said, considering the health risks associated with opioid painkillers, I strongly urge you to exhaust other options before resorting to these drugs. The good news is there are many natural alternatives to treating pain, including the following:

Medical cannabis

Medical marijuana has a long history as a natural analgesic and is now legal in 28 states. You can learn more about the laws in your state on medicalmarijuana.procon.org.30

Kratom

Kratom (Mitragyna speciose) is a plant remedy that has become a popular opioid substitute.31 In August 2016, the DEA issued a notice saying it was planning to ban kratom, listing it as Schedule 1 controlled substance.

However, following massive outrage from kratom users who say opioids are their only alternative, the agency reversed its decision.32 Still, its scheduling remains uncertain, as the U.S. Food and Drug Administration recently declared kratom an opioid.33

Kratom is safer than an opioid for someone in serious and chronic pain. However, it’s important to recognize that it is a psychoactive substance and should be used with great care. There’s very little research showing how to use it safely and effectively, and it may have a very different effect from one person to the next. The other issue to address is that there are a number of different strains available with different effects.

Also, while it may be useful for weaning people off opioids, kratom is in itself addictive. So, while it appears to be a far safer alternative to opioids, it’s still a powerful and potentially addictive substance. So please, do your own research before trying it.

Low-Dose Naltrexone (LDN)

Naltrexone is an opiate antagonist, originally developed in the early 1960s for the treatment of opioid addiction. When taken at very low doses (LDN, available only by prescription), it triggers endorphin production, which can boost your immune function and ease pain.

Curcumin: A primary therapeutic compound identified in the spice turmericcurcumin has been shown in more than 50 clinical studies to have potent anti-inflammatory activity. Curcumin is hard to absorb, so best results are achieved with preparations designed to improve absorption. It is very safe and you can take two to three every hour if you need to.
Astaxanthin: One of the most effective oil-soluble antioxidants known, astaxanthin has very potent anti-inflammatory properties. Higher doses are typically required for pain relief, and you may need 8 milligrams or more per day to achieve results.
Boswellia: Also known as boswellin or “Indian frankincense,” this herb contains powerful anti-inflammatory properties, which have been prized for thousands of years. This is one of my personal favorites, as it worked well for many of my former rheumatoid arthritis patients.
Bromelain: This protein-digesting enzyme, found in pineapples, is a natural anti-inflammatory. It can be taken in supplement form, but eating fresh pineapple may also be helpful. Keep in mind most of the bromelain is found within the core of the pineapple, so consider eating some of the pulpy core when you consume the fruit.
Cayenne cream: Also called capsaicin cream, this spice comes from dried hot peppers. It alleviates pain by depleting your body’s supply of substance P, a chemical component of nerve cells that transmit pain signals to your brain.
Cetyl myristoleate (CMO): This oil, found in dairy butter and fish, acts as a joint lubricant and anti-inflammatory. I have used a topical preparation of CMO to relieve ganglion cysts and a mild case of carpal tunnel syndrome.
Evening primrose, black currant and borage oils: These oils contain the fatty acid gamma-linolenic acid, which is useful for treating arthritic pain.
Ginger: This herb is anti-inflammatory and offers pain relief and stomach-settling properties. Fresh ginger works well steeped in boiling water as a tea, or incorporated into fresh vegetable juice.

The real reason some people become addicted to drugs

(The Conversation) Why do they do it? This is a question that friends and families often ask of those who are addicted.

It’s difficult to explain how drug addiction develops over time. To many, it looks like the constant search for pleasure. But the pleasure derived from opioids like heroin or stimulants like cocaine declines with repeated use. What’s more, some addictive drugs, like nicotine, fail to produce any noticeable euphoria in regular users.

So what does explain the persistence of addiction? As an addiction researcher for the past 15 years, I look to the brain to understand how recreational use becomes compulsive, prompting people like you and me to make bad choices.

Myths about addiction

There are two popular explanations for addiction, neither of which holds up to scrutiny.

The first is that compulsive drug taking is a bad habit – one that addicts just need to “kick.”

However, to the brain, a habit is nothing more than our ability to carry out repetitive tasks – like tying our shoelaces or brushing our teeth – more and more efficiently. People don’t typically get caught up in an endless and compulsive cycle of shoelace tying.

Another theory claims that overcoming withdrawal is too tough for many addicts. Withdrawal, the highly unpleasant feeling that occurs when the drug leaves your body, can include sweats, chills, anxiety and heart palpitations. For certain drugs, such as alcohol, withdrawal comes with a risk of death if not properly managed.

The painful symptoms of withdrawal are frequently cited as the reason addiction seems inescapable. However, even for heroin, withdrawal symptoms mostly subside after about two weeks. Plus, many addictive drugs produce varying and sometimes only mild withdrawal symptoms.

This is not to say that pleasure, habits or withdrawal are not involved in addiction. But we must ask whether they are necessary components of addiction – or whether addiction would persist even in their absence.

Recommended: How to Detoxify From Antibiotics and Other Chemical Antimicrobials

Pleasure versus desire

In the 1980s, researchers made a surprising discovery. Food, sex and drugs all appeared to cause dopamine to be released in certain areas of the brain, such as the nucleus accumbens.

This suggested to many in the scientific community that these areas were the brain’s pleasure centers and that dopamine was our own internal pleasure neurotransmitter. However, this idea has since been debunked. The brain does have pleasure centers, but they are not modulated by dopamine.

So what’s going on? It turns out that, in the brain, “liking” something and “wanting” something are two separate psychological experiences. “Liking” refers to the spontaneous delight one might experience eating a chocolate chip cookie. “Wanting” is our grumbling desire when we eye the plate of cookies in the center of the table during a meeting.

Dopamine is responsible for “wanting” – not for “liking.” For example, in one study, researchers observed rats that could not produce dopamine in their brains. These rats lost the urge to eat but still had pleasurable facial reactions when food was placed in their mouths.

All drugs of abuse trigger a surge of dopamine – a rush of “wanting” – in the brain. This makes us crave more drugs. With repeated drug use, the “wanting” grows, while our “liking” of the drug appears to stagnate or even decrease, a phenomenon known as tolerance.

In my own research, we looked at a small subregion of the amygdala, an almond-shaped brain structure best known for its role in fear and emotion. We found that activating this area makes rats more likely to show addictive-like behaviors: narrowing their focus, rapidly escalating their cocaine intake and even compulsively nibbling at a cocaine port. This subregion may be involved in excessive “wanting,” in humans, too, influencing us to make risky choices.

Recommended: How to Be Happy

Involuntary addicts

The recent opioid epidemic has produced what we might call “involuntary” addicts. Opioids – such as oxycodone, percocet, vicodin or fentanyl – are very effective at managing otherwise intractable pain. Yet they also produce surges in dopamine release.

Most individuals begin taking prescription opioids not for pleasure but rather from a need to manage their pain, often on the recommendation of a doctor. Any pleasure they may experience is rooted in the relief from pain.

However, over time, users tend to develop a tolerance. The drug becomes less and less effective, and they need larger doses of the drug to control pain. This exposes people to large surges of dopamine in the brain. As the pain subsides, they find themselves inexplicably hooked on a drug and compelled to take more.

The result of this regular intake of large amounts of drug is a hyperreactive “wanting” system. A sensitized “wanting” system triggers intense bouts of craving whenever in the presence of the drug or exposed to drug cues. These cues can include drug paraphernalia, negative emotions such as stress or even specific people and places. Drug cues are one of an addict’s biggest challenges.

These changes in the brain can be long-lasting, if not permanent. Some individuals seem to be more likely to undergo these changes. Research suggests that genetic factors may predispose certain individuals, which explains why a family history of addiction leads to increased risk. Early life stressors, such as childhood adversity or physical abuse, also seem to put people at more risk.

Recommended: Natural Remedies for Depression

Addiction and choice

Many of us regularly indulge in drugs of abuse, such as alcohol or nicotine. We may even occasionally overindulge. But, in most cases, this doesn’t qualify as addiction. This is, in part, because we manage to regain balance and choose alternative rewards like spending time with family or enjoyable drug-free hobbies.

However, for those susceptible to excessive “wanting,” it may be difficult to maintain that balance. Once researchers figure out what makes an individual susceptible to developing a hyperreactive “wanting” system, we can help doctors better manage the risk of exposing a patient to drugs with such potent addictive potential.

In the meantime, many of us should reframe how we think about addiction. Our lack of understanding of what predicts the risk of addiction means that it could just as easily have affected you or me. In many cases, the individual suffering from addiction doesn’t lack the willpower to quit drugs. They know and see the pain and suffering that it creates around them. Addiction simply creates a craving that’s often stronger than any one person could overcome alone.

That’s why people battling addiction deserve our support and compassion, rather than the distrust and exclusion that our society too often provides.

For the First Time, NFL Acknowledges Benefits of Cannabis, Offers to Study it for Pain

Doping in sports and steroid abuse concept with a american football, a bottle of prescription pills and syringes with green and red liquid on a dark background

(The Free Thought Project) The NFL is finally acknowledging that cannabis has the potential to treat acute and chronic pain. A report out today says that the NFL has sent a letter to the Player’s Association (NFLPA) indicating it is willing to study the use of medical cannabis for pain management.

The NFLPA, apparently quicker to grasp the conclusions of science, is already studying the issue. In Jan. 2017, the National Academies of Science (NAS) released an exhaustive study on the therapeutic benefits of cannabis, with chronic pain treatment being one of the most significant.

Related: Why Chronic Pain is Such a Pain and What You Can Do About It

Players in America’s favorite sport are plagued by pain, often for the rest of their lives, and many have already turned to medical cannabis whether the league allows it or not. Soon after the NAS study, retired football players were telling their stories of lives virtually ruined by pain and the standard drugs given to them such as opioid pills – only to find relief with cannabis.

Now, former NFL players are trying to open medical cannabis dispensaries and extolling the benefits of this medicinal plant. They are on the right side of history, and the NFL may finally be catching up.

Cannabis use remains banned by the league, with players regularly tested and penalized if THC is detected. At the moment, the NFL is still stuck in the Reefer Madness mentality, thinking that because federal government prohibits the plant, then they should as well. But the letter to the NFLPA is an encouraging sign.

We look forward to working with the Players Association on all issues involving the health and safety of our players,” said Joe Lockhart, the NFL’s executive vice president of communications…

The NFL, according to one person with knowledge of the matter, wrote a letter to the union asking if, given the NFLPA’s public comments on the issue this year, it is interested in working together on research. The league’s letter outlined a few areas for potential research that included pain management for both acute and chronic conditions.”
The NFLPA is also seeking to reduce punitive measures for the use of cannabis, which is especially needed now that recreational cannabis is legal in eight states and 26 other states have legalized medical use only.

I do think that issues of addressing it more in a treatment and less punitive measure is appropriate,” said DeMaurice Smith, NFLPA’s executive director. “I think it’s important to look at whether there are addiction issues. And I think it’s important to not simply assume recreation is the reason it’s being used.”

The issue of opioid abuse is another reason why the NFL should adopt a more reasonable approach to medical cannabis. Opiates are routinely handed out to players for acute and chronic pain, making them prone to join the ever-growing ranks of those addicted to these dangerous legal drugs. We know from multiple studies that people are giving up deadly, addictive opioids in favor of cannabis in states where it is legal.

In addition to a safer method of pain management, medical cannabis can help prevent brain damage, which is also pervasive in NFL players. A recent major study found that “a vast majority of the brains of deceased players that were studied showed signs of chronic traumatic encephalopathy, a degenerative condition linked to head trauma.”

Related: The Gut-Brain Connection

In response to this, Doctors for Cannabis Regulation is lobbying the NFL to change its irrational rules on cannabis. It should be noted that medical cannabis can be administered with no psychoactive effects.

There is some early data that cannabis does play a role in neuroprotection. This is the kind of science we’ve put in front of the NFL, hoping they would reconsider their antiquated policies,” Dr. Suzanne Sisley told The Chronicle. “The bottom line is that cannabinoids are clearly neuroprotective. We have preclinical data at the receptor level that cannabinoids and cannabis are not only involved with brain repair but neurogenesis, the development of new neural tissue. It’s one of the most exciting discoveries of modern neuroscience.”

The NFL appears to have taken the first step in embracing factual evidence and science. Hopefully this will continue, as other entities such as Big Pharma and the alcohol industry will surely lobby against relaxing the NFL’s current prohibitionist stance.